MedKoo Cat#: 592560 | Name: Metiprenaline

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Metiprenaline was developed as a bronchodilator.

Chemical Structure

Metiprenaline
Metiprenaline
CAS#1212-03-9 (free base)

Theoretical Analysis

MedKoo Cat#: 592560

Name: Metiprenaline

CAS#: 1212-03-9 (free base)

Chemical Formula: C12H19NO3

Exact Mass: 225.1365

Molecular Weight: 225.29

Elemental Analysis: C, 63.98; H, 8.50; N, 6.22; O, 21.30

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Synonym
Egyt 402; Egyt-402; Egyt402; Metiprenaline
IUPAC/Chemical Name
alpha-((Isopropylamino)methyl)vanillyl alcohol
InChi Key
XXCCGRRUBBGZRE-UHFFFAOYSA-N
InChi Code
InChI=1S/C12H19NO3/c1-8(2)13-7-11(15)9-4-5-10(14)12(6-9)16-3/h4-6,8,11,13-15H,7H2,1-3H3
SMILES Code
COC1=CC(C(O)CNC(C)C)=CC=C1O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 225.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Gründemann D, Köster S, Kiefer N, Breidert T, Engelhardt M, Spitzenberger F, Obermüller N, Schömig E. Transport of monoamine transmitters by the organic cation transporter type 2, OCT2. J Biol Chem. 1998 Nov 20;273(47):30915-20. PubMed PMID: 9812985. 2: Schömig E, Russ H, Staudt K, Martel F, Gliese M, Gründemann D. The extraneuronal monoamine transporter exists in human central nervous system glia. Adv Pharmacol. 1998;42:356-9. PubMed PMID: 9327915. 3: Obst OO, Rose H, Kammermeier H. Characterization of catecholamine uptake2 in isolated cardiac myocytes. Mol Cell Biochem. 1996 Oct-Nov;163-164:181-3. PubMed PMID: 8974055. 4: Streich S, Brüss M, Bönisch H. Expression of the extraneuronal monoamine transporter (uptake2) in human glioma cells. Naunyn Schmiedebergs Arch Pharmacol. 1996 Feb;353(3):328-33. PubMed PMID: 8692289. 5: Marino V, de la Lande IS, Newlyn M, Parker DA. Evidence for uptake2-mediated O-methylation of noradrenaline in the human amnion FL cell-line. Naunyn Schmiedebergs Arch Pharmacol. 1993 Apr;347(4):371-8. PubMed PMID: 8510765. 6: Marino V, de la Lande IS, Parker DA, Dally J, Wing S. Extraneuronal uptake of noradrenaline in rabbit dental pulp: evidence of identity with uptake1. Naunyn Schmiedebergs Arch Pharmacol. 1992 Aug;346(2):166-72. PubMed PMID: 1448181. 7: Bryan-Lluka LJ, Westwood NN, O'Donnell SR. Vascular uptake of catecholamines in perfused lungs of the rat occurs by the same process as Uptake1 in noradrenergic neurones. Naunyn Schmiedebergs Arch Pharmacol. 1992 Mar;345(3):319-26. PubMed PMID: 1535692. 8: Schömig E, Schönfeld CL. Extraneuronal noradrenaline transport (uptake2) in a human cell line (Caki-1 cells). Naunyn Schmiedebergs Arch Pharmacol. 1990 May;341(5):404-10. PubMed PMID: 2164161. 9: Schömig E, Babin-Ebell J, Schönfeld CL, Russ H, Trendelenburg U. Human Caki-1 cells are the first model for extraneuronal transport of noradrenaline (uptake2) which is based on a clonal cell line. J Neural Transm Suppl. 1990;32:437-40. PubMed PMID: 2089108. 10: Causon RC, Brown MJ, Davies DS. Reversed-phase high-performance liquid chromatography and amperometric detection of 3-O-methyl isoprenaline sulphate: application to studies on the presystemic metabolism of d-isoprenaline in man. J Chromatogr. 1985 Feb 8;337(2):311-20. PubMed PMID: 3988861.