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MedKoo Cat#: 592522 | Name: Aleuritic acid

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Aleuritic acid derivates have Anti-HIV activity.

Chemical Structure

Aleuritic acid
Aleuritic acid
CAS#17941-34-3

Theoretical Analysis

MedKoo Cat#: 592522

Name: Aleuritic acid

CAS#: 17941-34-3

Chemical Formula:

Exact Mass: 0.0000

Molecular Weight: 0.00

Elemental Analysis:

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Aleuritic acid
IUPAC/Chemical Name
(9S,10S)-9,10,16-trihydroxyhexadecanoic acid
InChi Key
MEHUJCGAYMDLEL-GJZGRUSLSA-N
InChi Code
InChI=1S/C16H32O5/c17-13-9-5-4-7-11-15(19)14(18)10-6-2-1-3-8-12-16(20)21/h14-15,17-19H,1-13H2,(H,20,21)/t14-,15-/m0/s1
SMILES Code
C(CCC[C@@H]([C@H](CCCCCCO)O)O)CCCC(=O)O
Appearance
TBD
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 0.00 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Guzman-Puyol S, Benítez JJ, Domínguez E, Bayer IS, Cingolani R, Athanassiou A, Heredia A, Heredia-Guerrero JA. Pectin-lipid self-assembly: influence on the formation of polyhydroxy fatty acids nanoparticles. PLoS One. 2015 Apr 27;10(4):e0124639. doi: 10.1371/journal.pone.0124639. eCollection 2015. PubMed PMID: 25915490; PubMed Central PMCID: PMC4411075. 2: Heredia-Guerrero JA, San-Miguel MA, Sansom MS, Heredia A, Benítez JJ. Aleuritic (9,10,16-trihydroxypalmitic) acid self-assembly on mica. Phys Chem Chem Phys. 2010 Sep 21;12(35):10423-8. doi: 10.1039/c0cp00163e. Epub 2010 Jul 6. PubMed PMID: 20603671. 3: Liu JB, Zhang Y, Cui BS, Cao YL, Yuan SP, Guo Y, Hou Q, Li S. Anti-HIV and NO production inhibition activities of epi-aleuritolic acid derivatives. J Asian Nat Prod Res. 2013;15(5):515-24. doi: 10.1080/10286020.2013.787990. Epub 2013 May 3. PubMed PMID: 23639006. 4: Wang L, Ishida Y, Ohtani H, Tsuge S, Nakayama T. Characterization of natural resin shellac by reactive pyrolysis-gas chromatography in the presence of organic alkali. Anal Chem. 1999 Apr 1;71(7):1316-22. doi: 10.1021/ac981049e. PubMed PMID: 21662952. 5: Ujváry I, Kis-Tamás A, Novák L. Simple and economic syntheses of some (Z)-7- and (Z)-9-alkenyl acetates, and of (E,Z)-7,9-dodecadien-1-yl acetate, the sex pheromone of the European grapevine moth, using aleuritic acid as a common starting material. J Chem Ecol. 1985 Jan;11(1):113-24. doi: 10.1007/BF00987610. PubMed PMID: 24311103. 6: Momo IJ, Dufat TH, Wandji J, Michel S, Chiozem DD. New triterpenoids from the stem bark of Hypodaphnis zenkeri. Nat Prod Res. 2013;27(2):137-45. doi: 10.1080/14786419.2012.662647. Epub 2012 Apr 11. PubMed PMID: 22493952. 7: McPhail AT, McPhail DR, Wani MC, Wall ME, Nicholas AW. Identity of maprounic acid with aleuritolic acid. Revision of the structure of maprounic acid: X-ray crystal structure of p-bromobenzyl acetylmaprounate. J Nat Prod. 1989 Jan-Feb;52(1):212-6. PubMed PMID: 2723669. 8: Heredia-Guerrero JA, Goldoni L, Benítez JJ, Davis A, Ceseracciu L, Cingolani R, Bayer IS, Heinze T, Koschella A, Heredia A, Athanassiou A. Cellulose-polyhydroxylated fatty acid ester-based bioplastics with tuning properties: Acylation via a mixed anhydride system. Carbohydr Polym. 2017 Oct 1;173:312-320. doi: 10.1016/j.carbpol.2017.05.068. Epub 2017 Jun 3. PubMed PMID: 28732871. 9: Chen Y, Tao S, Zeng F, Xie L, Shen Z. Antinociceptive and anti-inflammatory activities of Schefflera octophylla extracts. J Ethnopharmacol. 2015 Aug 2;171:42-50. doi: 10.1016/j.jep.2015.04.050. Epub 2015 May 2. PubMed PMID: 25944007. 10: Nyasse B, Ngantchou I, Nono JJ, Schneider B. Antifilarial activity in vitro of polycarpol and 3-O-acetyl aleuritolic acid from cameroonian medicinal plants against Onchocerca gutturosa. Nat Prod Res. 2006 Apr;20(4):391-7. PubMed PMID: 16644535. 11: Yang SM, Liu XK, Qing C, Wu DG, Zhu DY. Chemical constituents from the roots of Homonoia riparia. Yao Xue Xue Bao. 2007 Mar;42(3):292-6. PubMed PMID: 17520829. 12: Prasad SM, Ammon HL. Structure of (+-)-threo-9,10,16-trihydroxypalmitic acid. Acta Crystallogr C. 1989 Mar 15;45 ( Pt 3):465-7. PubMed PMID: 2610974. 13: Shiina I, Kubota M, Oshiumi H, Hashizume M. An effective use of benzoic anhydride and its derivatives for the synthesis of carboxylic esters and lactones: a powerful and convenient mixed anhydride method promoted by basic catalysts. J Org Chem. 2004 Mar 19;69(6):1822-30. PubMed PMID: 15058924. 14: Skrzypczynski Z, Wayland S. New reagents for the introduction of reactive functional groups into chemically synthesized DNA probes. Bioconjug Chem. 2003 May-Jun;14(3):642-52. PubMed PMID: 12757390. 15: Chaudhuri SK, Fullas F, Brown DM, Wani MC, Wall ME, Cai L, Mar W, Lee SK, Luo Y, Zaw K, et al. Isolation and structural elucidation of pentacyclic triterpenoids from Maprounea africana. J Nat Prod. 1995 Jan;58(1):1-9. PubMed PMID: 7760064. 16: Khiev P, Oh SR, Chae HS, Kwon OK, Ahn KS, Chin YW, Lee HK. Anti-inflammatory diterpene from Thyrsanthera suborbicularis. Chem Pharm Bull (Tokyo). 2011;59(3):382-4. PubMed PMID: 21372422. 17: Fröhlich JK, Froeder AL, Janovik V, Venturini TP, Pereira RP, Boligon AA, de Brum TF, Alves SH, da Rocha JB, Athayde ML. Antioxidant capacity, antimicrobial activity and triterpenes isolated from Jatropha isabellei Müll Arg. Nat Prod Res. 2013;27(12):1049-59. doi: 10.1080/14786419.2012.706296. Epub 2012 Jul 13. PubMed PMID: 22788721. 18: Peres MT, Delle Monache F, Cruz AB, Pizzolatti MG, Yunes RA. Chemical composition and antimicrobial activity of Croton urucurana Baillon (Euphorbiaceae). J Ethnopharmacol. 1997 May;56(3):223-6. PubMed PMID: 9201612. 19: Pattamadilok D, Suttisri R. Seco-terpenoids and other constituents from Elateriospermum tapos. J Nat Prod. 2008 Feb;71(2):292-4. doi: 10.1021/np070629g. Epub 2008 Jan 8. PubMed PMID: 18179177. 20: Reyes BM, Ramírez-Apan MT, Toscano RA, Delgado G. Triterpenes from Garcia parviflora. Cytotoxic evaluation of natural and semisynthetic friedelanes. J Nat Prod. 2010 Nov 29;73(11):1839-45. doi: 10.1021/np100440p. Epub 2010 Oct 19. PubMed PMID: 20958014.