Lanuginosine | CAS#23740-25-2 | aporphine alkaloid

MedKoo Cat#: 598386 | Name: Lanuginosine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Lanuginosine is an aporphine alkaloid. Lanuginosine exhibited cytotoxicity against U251.

Chemical Structure

Lanuginosine

CAS#23740-25-2

Theoretical Analysis

MedKoo Cat#: 598386

Name: Lanuginosine

CAS#: 23740-25-2

Chemical Formula: C18H11NO4

Exact Mass: 305.0688

Molecular Weight: 305.28

Elemental Analysis: C, 70.82; H, 3.63; N, 4.59; O, 20.96

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Lanuginosine; NSC 137553; NSC-137553; NSC137553; Oxoxylopin; Oxoxylopine;

IUPAC/Chemical Name

10-methoxy-8H-[1,3]dioxolo[4',5':4,5]benzo[1,2,3-de]benzo[g]quinolin-8-one

InChi Key

WLXLLQQGGGHOMA-UHFFFAOYSA-N

InChi Code

InChI=1S/C18H11NO4/c1-21-10-2-3-11-12(7-10)17(20)16-14-9(4-5-19-16)6-13-18(15(11)14)23-8-22-13/h2-7H,8H2,1H3

SMILES Code

O=C1C2=CC(OC)=CC=C2C3=C4OCOC4=CC5=CC=NC1=C53

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 305.28 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Menezes LR, Costa CO, Rodrigues AC, Santo FR, Nepel A, Dutra LM, Silva FM, Soares MB, Barison A, Costa EV, Bezerra DP. Cytotoxic Alkaloids from the Stem of Xylopia laevigata. Molecules. 2016 Jul 8;21(7). pii: E890. doi: 10.3390/molecules21070890. PubMed PMID: 27399666. 2: Mohamed SM, Hassan EM, Ibrahim NA. Cytotoxic and antiviral activities of aporphine alkaloids of Magnolia grandiflora L. Nat Prod Res. 2010 Sep;24(15):1395-402. doi: 10.1080/14786410902906959. PubMed PMID: 19764006. 3: Zhong SH, Fu YH, Zhou XM, Song XP, Chen GY. [Studies on alkaloids from Fissistigma oldhamii]. Zhongguo Zhong Yao Za Zhi. 2016 Aug;41(15):2838-2842. doi: 10.4268/cjcmm20161516. Chinese. PubMed PMID: 28914026. 4: Nieto M, Cavé A, Leboeuf M. [Alkaloids of the Annonaceae: composition of the bark of the trunk and roots of Enantia pilosa]. Lloydia. 1976 Sep-Oct;39(5):350-6. French. PubMed PMID: 1018620. 5: Barros LF, Ehrenfried CA, Riva D, Barison A, de Mello-Silva R, Stefanello ME. Essential oil and other constituents from Magnolia ovata fruit. Nat Prod Commun. 2012 Oct;7(10):1365-7. PubMed PMID: 23157012. 6: Wirasathien L, Pengsuparp T, Moriyasu M, Kawanishi K, Suttisri R. Cytotoxic C-benzylated chalcone and other constituents of Ellipeiopsis cherrevensis. Arch Pharm Res. 2006 Jun;29(6):497-502. PubMed PMID: 16833018. 7: Lu Z, Zhang Q, Chen R, Yu D. [Aporphine alkaloids from branches and leaves of Polyalthia nemoralis]. Zhongguo Zhong Yao Za Zhi. 2009 Sep;34(18):2343-5. Chinese. PubMed PMID: 20030084. 8: Zhang Z, ElSohly HN, Jacob MR, Pasco DS, Walker LA, Clark AM. New sesquiterpenoids from the root of Guatteria multivenia. J Nat Prod. 2002 Jun;65(6):856-9. PubMed PMID: 12088427. 9: Soni VK, Yadav DK, Bano N, Dixit P, Pathak M, Maurya R, Sahai M, Jain SK, Misra-Bhattacharya S. N-Methyl-6, 7-dimethoxyisoquinolone in Annona squamosa twigs is the major immune modifier to elicit polarized Th1 immune response in BALB/c mice. Fitoterapia. 2012 Jan;83(1):110-6. doi: 10.1016/j.fitote.2011.09.019. Epub 2011 Oct 8. PubMed PMID: 22004725. 10: Pyo MK, Yun-Choi HS, Hong YJ. Antiplatelet activities of aporphine alkaloids isolated from leaves of Magnolia obovata. Planta Med. 2003 Mar;69(3):267-9. PubMed PMID: 12677533.