MedKoo Cat#: 598358 | Name: Ganodermadiol

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Ganodermadiol is a lanostanoid isolated from Ganoderma lucidum.

Chemical Structure

Ganodermadiol
Ganodermadiol
CAS#104700-96-1

Theoretical Analysis

MedKoo Cat#: 598358

Name: Ganodermadiol

CAS#: 104700-96-1

Chemical Formula: C30H48O2

Exact Mass: 440.3654

Molecular Weight: 440.71

Elemental Analysis: C, 81.76; H, 10.98; O, 7.26

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Ganodermadiol; (+)-Ganoderol B; Ganoderol B;
IUPAC/Chemical Name
(3S,5R,10S,13R,14R,17R)-17-((R,E)-7-hydroxy-6-methylhept-5-en-2-yl)-4,4,10,13,14-pentamethyl-2,3,4,5,6,10,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
InChi Key
AOXXVRDKZLRGTJ-AZIDVCJLSA-N
InChi Code
InChI=1S/C30H48O2/c1-20(19-31)9-8-10-21(2)22-13-17-30(7)24-11-12-25-27(3,4)26(32)15-16-28(25,5)23(24)14-18-29(22,30)6/h9,11,14,21-22,25-26,31-32H,8,10,12-13,15-19H2,1-7H3/b20-9+/t21-,22-,25+,26+,28-,29-,30+/m1/s1
SMILES Code
CC1(C)[C@@H](O)CC[C@]2(C)C3=CC[C@]4(C)[C@@H]([C@H](C)CC/C=C(C)/CO)CC[C@](C)4C3=CC[C@@]12[H]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 440.71 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Arisawa M, Fujita A, Saga M, Fukumura H, Hayashi T, Shimizu M, Morita N. Three new lanostanoids from Ganoderma lucidum. J Nat Prod. 1986 Jul-Aug;49(4):621-5. PubMed PMID: 3783158. 2: Vazirian M, Faramarzi MA, Ebrahimi SE, Esfahani HR, Samadi N, Hosseini SA, Asghari A, Manayi A, Mousazadeh A, Asef MR, Habibi E, Amanzadeh Y. Antimicrobial effect of the Lingzhi or Reishi medicinal mushroom, Ganoderma lucidum (higher Basidiomycetes) and its main compounds. Int J Med Mushrooms. 2014;16(1):77-84. PubMed PMID: 24940906. 3: Mothana RA, Awadh Ali NA, Jansen R, Wegner U, Mentel R, Lindequist U. Antiviral lanostanoid triterpenes from the fungus Ganoderma pfeifferi. Fitoterapia. 2003 Feb;74(1-2):177-80. PubMed PMID: 12628419. 4: Li B, Lee DS, Kang Y, Yao NQ, An RB, Kim YC. Protective effect of ganodermanondiol isolated from the Lingzhi mushroom against tert-butyl hydroperoxide-induced hepatotoxicity through Nrf2-mediated antioxidant enzymes. Food Chem Toxicol. 2013 Mar;53:317-24. doi: 10.1016/j.fct.2012.12.016. Epub 2012 Dec 21. PubMed PMID: 23266269. 5: Gao JJ, Min BS, Ahn EM, Nakamura N, Lee HK, Hattori M. New triterpene aldehydes, lucialdehydes A-C, from Ganoderma lucidum and their cytotoxicity against murine and human tumor cells. Chem Pharm Bull (Tokyo). 2002 Jun;50(6):837-40. PubMed PMID: 12045343. 6: Dai J, Miller MA, Everetts NJ, Wang X, Li P, Li Y, Xu JH, Yao G. Elimination of quiescent slow-cycling cells via reducing quiescence depth by natural compounds purified from Ganoderma lucidum. Oncotarget. 2017 Feb 21;8(8):13770-13781. doi: 10.18632/oncotarget.14634. PubMed PMID: 28099150; PubMed Central PMCID: PMC5355137.