VU0463597, also known as ML-289, is a negative allosteric modulator of mGlu3 (IC50 = 0.66 μM) that displays 15-fold selectivity over mGlu2 and inactivity against mGlu5.1.
MedKoo Cat#: 532947
Name: VU0463597
CAS#: 1382481-79-9
Chemical Formula: C22H23NO3
Exact Mass: 349.1678
Molecular Weight: 349.43
Elemental Analysis: C, 75.62; H, 6.63; N, 4.01; O, 13.74
The following data is based on the product molecular weight 349.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |