Lanomycin | CAS#141363-91-9 | lanosterol 14alpha-demethylase inhibitor

MedKoo Cat#: 598305 | Name: Lanomycin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Lanomycin is isolated from Pycnidiophora dispersa; inhibits lanosterol 14alpha-demethylase.

Chemical Structure

Lanomycin

CAS#141363-91-9

Theoretical Analysis

MedKoo Cat#: 598305

Name: Lanomycin

CAS#: 141363-91-9

Chemical Formula: C17H27NO4

Exact Mass: 309.1940

Molecular Weight: 309.40

Elemental Analysis: C, 65.99; H, 8.80; N, 4.53; O, 20.68

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Lanomycin;

IUPAC/Chemical Name

(2R,3S,4R,5R)-4-methoxy-5-methyl-2-((2E,4E,6E)-octa-2,4,6-trien-2-yl)tetrahydro-2H-pyran-3-yl glycinate

InChi Key

DMLQRXAYJODTLF-XNMVBDESSA-N

InChi Code

InChI=1S/C17H27NO4/c1-5-6-7-8-9-12(2)16-17(22-14(19)10-18)15(20-4)13(3)11-21-16/h5-9,13,15-17H,10-11,18H2,1-4H3/b6-5+,8-7+,12-9+/t13-,15-,16-,17+/m1/s1

SMILES Code

NCC(O[C@@H]1[C@@H](/C(C)=C/C=C/C=C/C)OC[C@@H](C)[C@H]1OC)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 309.40 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: O'Sullivan J, Phillipson DW, Kirsch DR, Fisher SM, Lai MH, Trejo WH. Lanomycin and glucolanomycin, antifungal agents produced by Pycnidiophora dispersa. I. Discovery, isolation and biological activity. J Antibiot (Tokyo). 1992 Mar;45(3):306-12. PubMed PMID: 1577658. 2: Remsburg B, Phillipson DW, O'Sullivan J. Lanomycin and glucolanomycin, antifungal agents produced by Pycnidiophora dispersa. III. Biosynthesis of lanomycin: 13C NMR assignment and origin of the carbon skeleton. J Antibiot (Tokyo). 1992 Mar;45(3):420-3. PubMed PMID: 1577669. 3: Phillipson DW, O'Sullivan J, Johnson JH, Bolgar MS, Kahle AD. Lanomycin and glucolanomycin, antifungal agents produced by Pycnidiophora dispersa. II. Structure elucidation. J Antibiot (Tokyo). 1992 Mar;45(3):313-9. PubMed PMID: 1577659.