MedKoo Cat#: 572133 | Name: N-Boc-PEG4-bromide
Featured

Description:

WARNING: This product is for research use only, not for human or veterinary use.

N-Boc-PEG4-bromide is a PEG derivative containing a bromide group and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Chemical Structure

N-Boc-PEG4-bromide
N-Boc-PEG4-bromide
CAS#1392499-32-9

Theoretical Analysis

MedKoo Cat#: 572133

Name: N-Boc-PEG4-bromide

CAS#: 1392499-32-9

Chemical Formula: C15H30BrNO6

Exact Mass: 399.1257

Molecular Weight: 400.31

Elemental Analysis: C, 45.01; H, 7.55; Br, 19.96; N, 3.50; O, 23.98

Price and Availability

Size Price Availability Quantity
100mg USD 500.00
250mg USD 830.00
500mg USD 1,230.00
Bulk Inquiry
Buy Now
Add to Cart
Related CAS #
No Data
Synonym
N-Boc-PEG4-bromide
IUPAC/Chemical Name
tert-butyl (14-bromo-3,6,9,12-tetraoxatetradecyl)carbamate
InChi Key
KYOVSWOWVSWAII-UHFFFAOYSA-N
InChi Code
InChI=1S/C15H30BrNO6/c1-15(2,3)23-14(18)17-5-7-20-9-11-22-13-12-21-10-8-19-6-4-16/h4-13H2,1-3H3,(H,17,18)
SMILES Code
O=C(OC(C)(C)C)NCCOCCOCCOCCOCCBr
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 400.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Zhang P, Huang Y, Liu H, Marquez RT, Lu J, Zhao W, Zhang X, Gao X, Li J, Venkataramanan R, Xu L, Li S. A PEG-Fmoc conjugate as a nanocarrier for paclitaxel. Biomaterials. 2014 Aug;35(25):7146-56. doi: 10.1016/j.biomaterials.2014.04.108. Epub 2014 May 22. PubMed PMID: 24856103; PubMed Central PMCID: PMC4102141. 2: Salmaso S, Bersani S, Scomparin A, Mastrotto F, Scherpfer R, Tonon G, Caliceti P. Tailored PEG for rh-G-CSF analogue site-specific conjugation. Bioconjug Chem. 2009 Jun;20(6):1179-85. doi: 10.1021/bc9000432. PubMed PMID: 19469471.