Seproxetine HCl | CAS#127685-30-7 | fluoxetine enantiomer

MedKoo Cat#: 563411 | Name: Seproxetine HCl

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Seproxetine HCl is a more active enantiomer of N-desmethyl metabolite fluoxetine. It acts by selectively inhibiting the serotonin uptake carrier.

Chemical Structure

Seproxetine HCl

CAS#127685-30-7

Theoretical Analysis

MedKoo Cat#: 563411

Name: Seproxetine HCl

CAS#: 127685-30-7

Chemical Formula: C16H17ClF3NO

Exact Mass:

Molecular Weight: 331.76

Elemental Analysis: C, 57.93; H, 5.17; Cl, 10.69; F, 17.18; N, 4.22; O, 4.82

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Seproxetine hydrochloride; (S)-Norfluoxetine hydrochloride; (S)-Desmethylfluoxetine Hydrochloride;

IUPAC/Chemical Name

(S)-3-Phenyl-3-(4-(trifluoromethyl)phenoxy)propan-1-amine hydrochloride

InChi Key

GMTWWEPBGGXBTO-RSAXXLAASA-N

InChi Code

InChI=1S/C16H16F3NO.ClH/c17-16(18,19)13-6-8-14(9-7-13)21-15(10-11-20)12-4-2-1-3-5-12;/h1-9,15H,10-11,20H2;1H/t15-;/m0./s1

SMILES Code

NCC[C@@H](C1=CC=CC=C1)OC2=CC=C(C(F)(F)F)C=C2.[H]Cl

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 331.76 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Dawood S, Zarina S, Bano S. Docking studies of antidepressants against single crystal structure of tryptophan 2, 3-dioxygenase using Molegro Virtual Docker software. Pak J Pharm Sci. 2014 Sep;27(5 Spec no):1529-39. PubMed PMID: 25176248. 2: de Maat MM, Huitema AD, Mulder JW, Meenhorst PL, van Gorp EC, Mairuhu AT, Beijnen JH. Drug Interaction of Fluvoxamine and Fluoxetine with Nevirapine in HIV-1-Infected Individuals. Clin Drug Investig. 2003;23(10):629-37. PubMed PMID: 17535078.