Lab 170250F | CAS#88630-25-5 | cytochrome inhibitor

MedKoo Cat#: 598188 | Name: Lab 170250F

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Lab 170250F is a potent inhibitor of cytochrome P-450-obtusifoliol-14-demethylase.

Chemical Structure

Lab 170250F

CAS#88630-25-5

Theoretical Analysis

MedKoo Cat#: 598188

Name: Lab 170250F

CAS#: 88630-25-5

Chemical Formula: C17H14ClN3O

Exact Mass: 311.0825

Molecular Weight: 311.76

Elemental Analysis: C, 65.49; H, 4.53; Cl, 11.37; N, 13.48; O, 5.13

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Lab 170250F; Lab-170250F; Lab170250F;

IUPAC/Chemical Name

1-((2-(4-chlorophenyl)-3-phenyloxiran-2-yl)methyl)-1H-1,2,4-triazole

InChi Key

YGLGKNIVFJHGIW-UHFFFAOYSA-N

InChi Code

InChI=1S/C17H14ClN3O/c18-15-8-6-14(7-9-15)17(10-21-12-19-11-20-21)16(22-17)13-4-2-1-3-5-13/h1-9,11-12,16H,10H2

SMILES Code

ClC1=CC=C(C2(CN3N=CN=C3)OC2C4=CC=CC=C4)C=C1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 311.76 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Grausem B, Chaubet N, Gigot C, Loper JC, Benveniste P. Functional expression of Saccharomyces cerevisiae CYP51A1 encoding lanosterol-14-demethylase in tobacco results in bypass of endogenous sterol biosynthetic pathway and resistance to an obtusifoliol-14-demethylase herbicide inhibitor. Plant J. 1995 May;7(5):761-70. PubMed PMID: 7773307. 2: Maillot-Vernier P, Schaller H, Benveniste P, Belliard G. Biochemical characterization of a sterol mutant plant regenerated from a tobacco callus resistant to a triazole cytochrome-P-450-obtusifoliol-14-demethylase inhibitor. Biochem Biophys Res Commun. 1989 Nov 30;165(1):125-30. PubMed PMID: 2590214. 3: Maillot-Vernier P, Gondet L, Schaller H, Benveniste P, Belliard G. Genetic study and further biochemical characterization of a tobacco mutant that overproduces sterols. Mol Gen Genet. 1991 Dec;231(1):33-40. PubMed PMID: 1753944.