Pyroglutamylvaline | CAS#21282-10-0 | dipeptide

MedKoo Cat#: 598127 | Name: Pyroglutamylvaline

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Pyroglutamylvaline also known as pyro-Glu-Val or 5-oxoprolylvaline, is classified as a member of the dipeptides. Dipeptides are organic compounds containing a sequence of exactly two alpha-amino acids joined by a peptide bond. Pyroglutamylvaline is considered to be practically insoluble (in water) and acidic.

Chemical Structure

Pyroglutamylvaline

CAS#21282-10-0

Theoretical Analysis

MedKoo Cat#: 598127

Name: Pyroglutamylvaline

CAS#: 21282-10-0

Chemical Formula: C10H16N2O4

Exact Mass: 228.1110

Molecular Weight: 228.24

Elemental Analysis: C, 52.62; H, 7.07; N, 12.27; O, 28.04

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

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Synonym

Pyro-glu-val; Pyroglutamyl valine; Pyroglutamylvaline; Pyroglutamyl-valine;

IUPAC/Chemical Name

((S)-5-oxopyrrolidine-2-carbonyl)-L-valine

InChi Key

DTSWLLBBGHRXQH-XPUUQOCRSA-N

InChi Code

InChI=1S/C10H16N2O4/c1-5(2)8(10(15)16)12-9(14)6-3-4-7(13)11-6/h5-6,8H,3-4H2,1-2H3,(H,11,13)(H,12,14)(H,15,16)/t6-,8-/m0/s1

SMILES Code

CC(C)[C@@H](C(O)=O)NC([C@H](CC1)NC1=O)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 228.24 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Fujiwara K, Kitagawa T, Tsuru D. Inactivation of pyroglutamyl aminopeptidase by L-pyroglutamyl chloromethyl ketone. Biochim Biophys Acta. 1981 Mar 13;658(1):10-6. PubMed PMID: 6111350. 2: Fujiwara K, Matsumoto E, Kitagawa T, Tsuru D. Inactivation of pyroglutamyl aminopeptidase by N alpha-carbobenzoxy-L-pyroglutamyl chloromethyl ketone. J Biochem. 1981 Aug;90(2):433-7. PubMed PMID: 6117551. 3: Fujiwara K, Matsumoto E, Kitagawa T, Tsuru D. N-alpha-carbobenzoxy pyroglutamyl diazomethyl ketone as active-site-directed inhibitor for pyroglutamyl peptidase. Biochim Biophys Acta. 1982 Apr 3;702(2):149-54. PubMed PMID: 6123347.