t-Boc-N-Amido-PEG2-azide is a PEG derivative containing an azide group and Boc-protected amino group. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The Boc group can be deprotected under mild acidic conditions to form the free amine. PEG Linkers may be useful in the development of antibody drug conjugates.
MedKoo Cat#: 572116
Name: t-Boc-N-Amido-PEG2-azide
CAS#: 950683-55-3
Chemical Formula: C11H22N4O4
Exact Mass: 274.1641
Molecular Weight: 274.32
Elemental Analysis: C, 48.16; H, 8.08; N, 20.42; O, 23.33
The following data is based on the product molecular weight 274.32 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
