MedKoo Cat#: 592152 | Name: Fagaramide

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Fagaramide has Antiplasmodial activity.

Chemical Structure

Fagaramide
Fagaramide
CAS#60045-88-7

Theoretical Analysis

MedKoo Cat#: 592152

Name: Fagaramide

CAS#: 60045-88-7

Chemical Formula: C14H17NO3

Exact Mass: 247.1208

Molecular Weight: 247.29

Elemental Analysis: C, 68.00; H, 6.93; N, 5.66; O, 19.41

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Fagaramide; AI3-30755; AI3 30755; AI330755
IUPAC/Chemical Name
2-Propenamide, 3-(1,3-benzodioxol-5-yl)-N-(2-methylpropyl)-
InChi Key
WKWYNAMJWDRHBP-GQCTYLIASA-N
InChi Code
InChI=1S/C14H17NO3/c1-10(2)8-15-14(16)6-4-11-3-5-12-13(7-11)18-9-17-12/h3-7,10H,8-9H2,1-2H3,(H,15,16)/b6-4+
SMILES Code
O=C(NCC(C)C)/C=C/C1=CC=C(OCO2)C2=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 247.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Adia MM, Emami SN, Byamukama R, Faye I, Borg-Karlson AK. Antiplasmodial activity and phytochemical analysis of extracts from selected Ugandan medicinal plants. J Ethnopharmacol. 2016 Jun 20;186:14-19. doi: 10.1016/j.jep.2016.03.047. Epub 2016 Mar 24. PubMed PMID: 27019273. 2: Anyanwu GO, Nisar-ur-Rehman, Onyeneke CE, Rauf K. Medicinal plants of the genus Anthocleista--A review of their ethnobotany, phytochemistry and pharmacology. J Ethnopharmacol. 2015 Dec 4;175:648-67. doi: 10.1016/j.jep.2015.09.032. Epub 2015 Nov 11. Review. PubMed PMID: 26432351. 3: Neal JJ. Myristicin, safrole, and fagaramide as phytosynergists of xanthotoxin. J Chem Ecol. 1989 Jan;15(1):309-15. doi: 10.1007/BF02027792. PubMed PMID: 24271445. 4: Ayofor JF, Ngadjui BT, Sondengam BL, Tsamo E. A Contribution to the Phytochemistry of Zanthoxylum tessmannii1. Planta Med. 1984 Jun;50(3):210-2. PubMed PMID: 17340299. 5: Moody JO, Sofowora A. Leaf Alkaloids of Zanthoxylum rubescens. Planta Med. 1984 Feb;50(1):101-3. PubMed PMID: 17340264. 6: Oriowo MA. Anti-inflammatory activity of piperonyl-4-acrylic isobutyl amide, an extractive from Zanthoxylum zanthoxyloides. Planta Med. 1982 Jan;44(1):54-6. PubMed PMID: 7063561. 7: Essien EM, Okogun JI. Effect of the root extract of Fagara zanthoxyloides on blood coagulation. Thromb Haemost. 1976 Dec 31;36(3):525-31. PubMed PMID: 1037149.