MedKoo Cat#: 572107 | Name: t-Boc-N-amido-PEG2-CH2CO2H
Featured

Description:

WARNING: This product is for research use only, not for human or veterinary use.

t-Boc-N-amido-PEG2-CH2CO2H is a PEG derivative containing a terminal carboxylic acid and Boc-protected amino group. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Chemical Structure

t-Boc-N-amido-PEG2-CH2CO2H
t-Boc-N-amido-PEG2-CH2CO2H
CAS#108466-89-3

Theoretical Analysis

MedKoo Cat#: 572107

Name: t-Boc-N-amido-PEG2-CH2CO2H

CAS#: 108466-89-3

Chemical Formula: C11H21NO6

Exact Mass: 263.1369

Molecular Weight: 263.29

Elemental Analysis: C, 50.18; H, 8.04; N, 5.32; O, 36.46

Price and Availability

Size Price Availability Quantity
1g USD 340.00
5g USD 1,000.00
Bulk Inquiry
Buy Now
Add to Cart
Related CAS #
No Data
Synonym
t-Boc-N-amido-PEG2-CH2CO2H
IUPAC/Chemical Name
2,2-dimethyl-4-oxo-3,8,11-trioxa-5-azatridecan-13-oic acid
InChi Key
OMBVJVWVXRNDSL-UHFFFAOYSA-N
InChi Code
InChI=1S/C11H21NO6/c1-11(2,3)18-10(15)12-4-5-16-6-7-17-8-9(13)14/h4-8H2,1-3H3,(H,12,15)(H,13,14)
SMILES Code
CC(C)(C)OC(NCCOCCOCC(O)=O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info
The hydrophilic PEG spacer increases solubility in aqueous media.

Preparing Stock Solutions

The following data is based on the product molecular weight 263.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Zhang P, Huang Y, Liu H, Marquez RT, Lu J, Zhao W, Zhang X, Gao X, Li J, Venkataramanan R, Xu L, Li S. A PEG-Fmoc conjugate as a nanocarrier for paclitaxel. Biomaterials. 2014 Aug;35(25):7146-56. doi: 10.1016/j.biomaterials.2014.04.108. Epub 2014 May 22. PubMed PMID: 24856103; PubMed Central PMCID: PMC4102141. 2: Salmaso S, Bersani S, Scomparin A, Mastrotto F, Scherpfer R, Tonon G, Caliceti P. Tailored PEG for rh-G-CSF analogue site-specific conjugation. Bioconjug Chem. 2009 Jun;20(6):1179-85. doi: 10.1021/bc9000432. PubMed PMID: 19469471.