N-(4,6-divinyl-1,3,5-triazin-2-yl)-PEG4-TCO is a novel cysteine binder coupled to a terminal TCO bound by a PEG linker. The divinyltriazine works by stapling of two cysteine residues to form macrocyclic peptides from their unprotected linear counterparts. The hydrophilic PEG spacer increases solubility in aqueous media. This reagent can be used to label antibodies, proteins and other primary amine-containing macromolecules with TCO moiety.
MedKoo Cat#: 122098
Name: N-(4,6-divinyl-1,3,5-triazin-2-yl)-PEG4-TCO
CAS#: N/A
Chemical Formula: C29H46N6O7
Exact Mass: 590.3428
Molecular Weight: 590.72
Elemental Analysis: C, 58.96; H, 7.85; N, 14.23; O, 18.96
The following data is based on the product molecular weight 590.72 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |