Cyclopeptolide 1 | CAS#129816-38-2 | antifungal cyclopeptolide

MedKoo Cat#: 598055 | Name: Cyclopeptolide 1

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Cyclopeptolide 1 is a novel antifungal cyclopeptolide. Cyclopeptolide 1 has a remote similarity to cyclosporin A; consists of nine S-amino acids and R-lactic acid.

Chemical Structure

Cyclopeptolide 1

CAS#129816-38-2

Theoretical Analysis

MedKoo Cat#: 598055

Name: Cyclopeptolide 1

CAS#: 129816-38-2

Chemical Formula: C57H91N9O14

Exact Mass: 1125.6685

Molecular Weight: 1126.40

Elemental Analysis: C, 60.78; H, 8.14; N, 11.19; O, 19.89

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Cyclopeptolide 1; SDZ 90-215; Cyclopeptolide-1;

IUPAC/Chemical Name

2-((3S,6S,9S,12S,15S,21S,24S,27R,33aS)-12,15-di((S)-sec-butyl)-3,6,21-triisopropyl-24-(4-methoxybenzyl)-2,8,11,14,20,27-hexamethyl-1,4,7,10,13,16,19,22,25,28-decaoxodotriacontahydropyrido[2,1-a1][1]oxa[4,7,10,13,16,19,22,25,28]nonaazacyclotriacontin-9-yl)acetic acid

InChi Key

WRIUTPDMSISMSW-OJCSTHIPSA-N

InChi Code

InChI=1S/C57H91N9O14/c1-18-34(9)47-49(70)58-30-42(67)62(13)45(32(5)6)50(71)59-39(28-37-23-25-38(79-17)26-24-37)57(78)80-36(11)52(73)66-27-21-20-22-40(66)53(74)63(14)46(33(7)8)51(72)60-44(31(3)4)55(76)61(12)41(29-43(68)69)54(75)65(16)48(35(10)19-2)56(77)64(47)15/h23-26,31-36,39-41,44-48H,18-22,27-30H2,1-17H3,(H,58,70)(H,59,71)(H,60,72)(H,68,69)/t34-,35-,36+,39-,40-,41-,44-,45-,46-,47-,48-/m0/s1

SMILES Code

O=C(N1[C@@H](CCCC1)C(N(C)[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N(C)[C@@H](CC(O)=O)C(N(C)[C@H]2[C@@H](C)CC)=O)=O)=O)=O)[C@@H](C)OC([C@H](Cc3ccc(OC)cc3)NC([C@H](C(C)C)N(C)C(CNC([C@H]([C@@H](C)CC)N(C)C2=O)=O)=O)=O)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 1,126.40 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Emmer G, Grassberger MA, Meingassner JG, Schulz G, Schaude M. Derivatives of a novel cyclopeptolide. 1. Synthesis, antifungal activity, and structure-activity relationships. J Med Chem. 1994 Jun 24;37(13):1908-17. PubMed PMID: 8027972. 2: Yun BS, Kwon EM, Kim JC, Yu SH. Antifungal cyclopeptolide from fungal saprophytic antagonist Ulocladium atrum. J Microbiol Biotechnol. 2007 Jul;17(7):1217-20. PubMed PMID: 18051337.