MedKoo Cat#: 598046 | Name: Astiron

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Astiron is a self-expanding bare-metal nitinol stent.

Chemical Structure

Astiron
Astiron
CAS#1620-24-2

Theoretical Analysis

MedKoo Cat#: 598046

Name: Astiron

CAS#: 1620-24-2

Chemical Formula: C26H33Cl2N3O5

Exact Mass: 537.1797

Molecular Weight: 538.46

Elemental Analysis: C, 58.00; H, 6.18; Cl, 13.17; N, 7.80; O, 14.86

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
Astiron; Astyron;
IUPAC/Chemical Name
ethyl (2-acetamido-3-(4-(bis(2-chloroethyl)amino)phenyl)propanoyl)-L-tyrosinate
InChi Key
SULYQGVAYSECAW-CGAIIQECSA-N
InChi Code
InChI=1S/C26H33Cl2N3O5/c1-3-36-26(35)24(17-20-6-10-22(33)11-7-20)30-25(34)23(29-18(2)32)16-19-4-8-21(9-5-19)31(14-12-27)15-13-28/h4-11,23-24,33H,3,12-17H2,1-2H3,(H,29,32)(H,30,34)/t23?,24-/m0/s1
SMILES Code
OC1=CC=C(C=C1)C[C@@H](C(OCC)=O)NC(C(CC2=CC=C(N(CCCl)CCCl)C=C2)NC(C)=O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 538.46 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Burket MW, Brodmann M, Metzger C, Tan K, Jaff MR. Twelve-Month Results of the Nitinol Astron Stent in Iliac Artery Lesions. J Vasc Interv Radiol. 2016 Nov;27(11):1650-1656.e1. doi: 10.1016/j.jvir.2016.06.008. Epub 2016 Aug 16. PubMed PMID: 27542591. 2: Prasad P, Wijnholds SJ. Amsterdam-ASTRON radio transient facility and analysis centre: towards a 24 x 7, all-sky monitor for the low-frequency array (LOFAR). Philos Trans A Math Phys Eng Sci. 2013 Apr 29;371(1992):20120234. doi: 10.1098/rsta.2012.0234. Print 2013 Jun 13. PubMed PMID: 23630370. 3: Tulachka GJ, Moser JB, Taylor RL. A comparison of Astron L.C. and Triad VLC2: a preliminary report. Northwest Dent Res. 1989 Spring;1(1):17-8. PubMed PMID: 2627365. 4: Schmidt W, Wissgott C, Andresen R, Behrens P, Schmitz KP. Performance characteristics of modern self-expanding nitinol stents indicated for SFA. Rofo. 2011 Sep;183(9):818-25. doi: 10.1055/s-0031-1273445. Epub 2011 Jul 12. PubMed PMID: 21751121. 5: Jones AP, Ysard N, Köhler M, Fanciullo L, Bocchio M, Micelotta E, Verstraete L, Guillet V. The cycling of carbon into and out of dust. Faraday Discuss. 2014;168:313-26. PubMed PMID: 25302387. 6: Neininger N, Dumke M. Intergalactic cold dust in the NGC 4631 group. Proc Natl Acad Sci U S A. 1999 May 11;96(10):5360-5. PubMed PMID: 10318888; PubMed Central PMCID: PMC21864. 7: Kelly JF, McGough RJ. Approximate analytical time-domain Green's functions for the Caputo fractional wave equation. J Acoust Soc Am. 2016 Aug;140(2):1039. doi: 10.1121/1.4960549. PubMed PMID: 27586735. 8: Kellerer AN, Ribak EN. Beyond the diffraction limit via optical amplification. Opt Lett. 2016 Jul 15;41(14):3181-4. doi: 10.1364/OL.41.003181. PubMed PMID: 27420490. 9: Bosiers M, Deloose K, Callaert J, Keirse K, Verbist J, Hendriks J, Lauwers P, D'Archambeau O, Scheinert D, Torsello G, Peeters P. 4-French-compatible endovascular material is safe and effective in the treatment of femoropopliteal occlusive disease: results of the 4-EVER trial. J Endovasc Ther. 2013 Dec;20(6):746-56. doi: 10.1583/13-4437MR.1. PubMed PMID: 24325689. 10: Martínez-Sykora J, De Pontieu B, Hansteen V, Carlsson M. The role of partial ionization effects in the chromosphere. Philos Trans A Math Phys Eng Sci. 2015 May 28;373(2042). pii: 20140268. doi: 10.1098/rsta.2014.0268. PubMed PMID: 25897096; PubMed Central PMCID: PMC4410556. 11: Schulte KL, Pilger E, Schellong S, Tan KT, Baumann F, Langhoff R, Torsello G, Zeller T, Amendt K, Brodmann M; EXPAND Investigators. Primary Self-EXPANDing Nitinol Stenting vs Balloon Angioplasty With Optional Bailout Stenting for the Treatment of Infrapopliteal Artery Disease in Patients With Severe Intermittent Claudication or Critical Limb Ischemia (EXPAND Study). J Endovasc Ther. 2015 Oct;22(5):690-7. doi: 10.1177/1526602815598955. Epub 2015 Aug 5. PubMed PMID: 26245919. 12: Latta MA, Tateosian LH. Comparison of two light cured reline systems. J Clin Dent. 1989 Spring;1(4):116-20. PubMed PMID: 2639689. 13: Tadhunter C, Morganti R, Rose M, Oonk JB, Oosterloo T. Jet acceleration of the fast molecular outflows in the Seyfert galaxy IC 5063. Nature. 2014 Jul 24;511(7510):440-3. doi: 10.1038/nature13520. Epub 2014 Jul 6. PubMed PMID: 25043049. 14: Harwood JJ, Croston JH, Intema HT, Stewart AJ, Ineson J, Hardcastle MJ, Godfrey L, Best P, Brienza M, Heesen V, Mahony EK, Morganti R, Murgia M, Orrú E, Röttgering H, Shulevski A, Wise MW. FR II radio galaxies at low frequencies - I. Morphology, magnetic field strength and energetics. Mon Not R Astron Soc. 2016 Mar 17;458(4):4443-4455. eCollection 2016 Jun 1. PubMed PMID: 27284270. 15: Sarkadi H, Bérczi V, Kollár A, Kiss D, Jakabfi P, Végh EM, Nemes B, Merkely B, Hüttl K, Dósa E. Safety, clinical outcome, and fracture rate of femoropopliteal stenting using a 4F compatible delivery system. Eur J Vasc Endovasc Surg. 2015 Feb;49(2):199-204. doi: 10.1016/j.ejvs.2014.12.004. Epub 2015 Jan 8. PubMed PMID: 25579877. 16: Keane EF, Johnston S, Bhandari S, Barr E, Bhat ND, Burgay M, Caleb M, Flynn C, Jameson A, Kramer M, Petroff E, Possenti A, van Straten W, Bailes M, Burke-Spolaor S, Eatough RP, Stappers BW, Totani T, Honma M, Furusawa H, Hattori T, Morokuma T, Niino Y, Sugai H, Terai T, Tominaga N, Yamasaki S, Yasuda N, Allen R, Cooke J, Jencson J, Kasliwal MM, Kaplan DL, Tingay SJ, Williams A, Wayth R, Chandra P, Perrodin D, Berezina M, Mickaliger M, Bassa C. The host galaxy of a fast radio burst. Nature. 2016 Feb 25;530(7591):453-6. doi: 10.1038/nature17140. PubMed PMID: 26911781. 17: Bjerkeli P, van der Wiel MH, Harsono D, Ramsey JP, Jørgensen JK. Resolved images of a protostellar outflow driven by an extended disk wind. Nature. 2016 Dec 14;540(7633):406-409. doi: 10.1038/nature20600. PubMed PMID: 27974756. 18: Wylie SJ, Zhang C, Long V, Roossinck MJ, Koh SH, Jones MG, Iqbal S, Li H. Differential responses to virus challenge of laboratory and wild accessions of australian species of nicotiana, and comparative analysis of RDR1 gene sequences. PLoS One. 2015 Mar 30;10(3):e0121787. doi: 10.1371/journal.pone.0121787. eCollection 2015. PubMed PMID: 25822508; PubMed Central PMCID: PMC4379023. 19: Bird MI, O'Grady D, Ulm S. Humans, water, and the colonization of Australia. Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):11477-11482. Epub 2016 Sep 26. PubMed PMID: 27671630; PubMed Central PMCID: PMC5068313. 20: Chen SC, Telinius N, Lin HT, Huang MC, Lin CC, Chou CH, Hjortdal J. Use of Fish Scale-Derived BioCornea to Seal Full-Thickness Corneal Perforations in Pig Models. PLoS One. 2015 Nov 24;10(11):e0143511. doi: 10.1371/journal.pone.0143511. eCollection 2015. PubMed PMID: 26599018; PubMed Central PMCID: PMC4657996.