PD-151307 | CAS#225925-12-2 | calcium channel blocker

MedKoo Cat#: 598036 | Name: PD-151307

Description:

WARNING: This product is for research use only, not for human or veterinary use.

PD-151307 is an N-type calcium channel blocker.

Chemical Structure

PD-151307

CAS#225925-12-2

Theoretical Analysis

MedKoo Cat#: 598036

Name: PD-151307

CAS#: 225925-12-2

Chemical Formula: C33H47N3O5

Exact Mass: 565.3516

Molecular Weight: 565.75

Elemental Analysis: C, 70.06; H, 8.37; N, 7.43; O, 14.14

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

PD-151307; PD 151307; PD151307;

IUPAC/Chemical Name

tert-butyl (S)-2-((S)-2-(azepane-1-carboxamido)-4-methylpentanamido)-3-(4-(benzyloxy)phenyl)propanoate

InChi Key

NDGCCFMKWNNCLD-VMPREFPWSA-N

InChi Code

InChI=1S/C33H47N3O5/c1-24(2)21-28(35-32(39)36-19-11-6-7-12-20-36)30(37)34-29(31(38)41-33(3,4)5)22-25-15-17-27(18-16-25)40-23-26-13-9-8-10-14-26/h8-10,13-18,24,28-29H,6-7,11-12,19-23H2,1-5H3,(H,34,37)(H,35,39)/t28-,29-/m0/s1

SMILES Code

O=C(OC(C)(C)C)[C@H](CC1=CC=C(OCC2=CC=CC=C2)C=C1)NC([C@H](CC(C)C)NC(N3CCCCCC3)=O)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 565.75 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Ryder TR, Hu LY, Rafferty MF, Millerman E, Szoke BG, Tarczy-Hornoch K. Multiple parallel synthesis of N,N-dialkyldipeptidylamines as N-type calcium channel blockers. Bioorg Med Chem Lett. 1999 Jul 5;9(13):1813-8. PubMed PMID: 10406647. 2: Ryder TR, Hu LY, Rafferty MF, Lotarski SM, Rock DM, Stoehr SJ, Taylor CP, Weber ML, Miljanich GP, Millerman E, Szoke BG. Structure-activity relationship at the leucine side chain in a series of N,N-dialkyldipeptidyl-amines as N-type calcium channel blockers. Drug Des Discov. 2000;16(4):317-22. PubMed PMID: 10807036.