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MedKoo Cat#: 563335 | Name: EGA
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

EGA is a selective inhibitor of endosomol trafficking pathways exploited by multiple toxins and virus.

Chemical Structure

EGA
EGA
CAS#415687-81-9

Theoretical Analysis

MedKoo Cat#: 563335

Name: EGA

CAS#: 415687-81-9

Chemical Formula: C16H16BrN3O

Exact Mass: 345.0477

Molecular Weight: 346.22

Elemental Analysis: C, 55.51; H, 4.66; Br, 23.08; N, 12.14; O, 4.62

Price and Availability

Size Price Availability Quantity
5mg USD 350.00 2 Weeks
10mg USD 550.00 2 Weeks
25mg USD 950.00 2 Weeks
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Related CAS #
No Data
Synonym
EGA;
IUPAC/Chemical Name
4-Bromobenzaldehyde N4-(2,6-dimethyl)phenylsemicarbazone
InChi Key
QVNLLEFLGISSAQ-VCHYOVAHSA-N
InChi Code
InChI=1S/C16H16BrN3O/c1-11-4-3-5-12(2)15(11)19-16(21)20-18-10-13-6-8-14(17)9-7-13/h3-10H,1-2H3,(H2,19,20,21)/b18-10+
SMILES Code
BrC1=CC=C(C=C1)/C=N/NC(NC2=C(C)C=CC=C2C)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 346.22 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
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PubMed PMID: 29967696; PubMed Central PMCID: PMC6008623. 4: Lusito E, Felice B, D'Ario G, Ogier A, Montani F, Di Fiore PP, Bianchi F. Unraveling the role of low-frequency mutated genes in breast cancer. Bioinformatics. 2018 Jun 29. doi: 10.1093/bioinformatics/bty520. [Epub ahead of print] PubMed PMID: 29961866. 5: Kumar M, Bansal N. Ellagic acid prevents dementia through modulation of PI3-kinase-endothelial nitric oxide synthase signalling in streptozotocin-treated rats. Naunyn Schmiedebergs Arch Pharmacol. 2018 Jun 15. doi: 10.1007/s00210-018-1524-2. [Epub ahead of print] PubMed PMID: 29947909. 6: MacGregor EA, Guillebaud J. The 7-day contraceptive hormone-free interval should be consigned to history. BMJ Sex Reprod Health. 2018 Jun 26. pii: bmjsrh-2017-200036. doi: 10.1136/bmjsrh-2017-200036. [Epub ahead of print] PubMed PMID: 29945924. 7: Barrachina F, Anastasiadi D, Jodar M, Castillo J, Estanyol JM, Piferrer F, Oliva R. Identification of a complex population of chromatin-associated proteins in the European sea bass (Dicentrarchus labrax) sperm. Syst Biol Reprod Med. 2018 Jun 25:1-16. doi: 10.1080/19396368.2018.1482383. [Epub ahead of print] PubMed PMID: 29939100. 8: Grarup N, Moltke I, Andersen MK, Bjerregaard P, Larsen CVL, Dahl-Petersen IK, Jørsboe E, Tiwari HK, Hopkins SE, Wiener HW, Boyer BB, Linneberg A, Pedersen O, Jørgensen ME, Albrechtsen A, Hansen T. Identification of novel high-impact recessively inherited type 2 diabetes risk variants in the Greenlandic population. Diabetologia. 2018 Jun 20. doi: 10.1007/s00125-018-4659-2. [Epub ahead of print] PubMed PMID: 29926116. 9: Liu X, Luo C, Deng K, Wu Z, Wei Y, Jiang J, Lu F, Shi D. Cytoplasmic volume of recipient oocytes affects the nucleus reprogramming and the developmental competence of HMC buffalo (Bubalus bubalis) embryos. J Vet Med Sci. 2018 Jun 20. doi: 10.1292/jvms.18-0043. [Epub ahead of print] PubMed PMID: 29925699. 10: Magnadóttir B, Hayes P, Hristova M, Bragason BT, Nicholas AP, Dodds AW, Guðmundsdóttir S, Lange S. Post-translational protein deimination in cod (Gadus morhua L.) ontogeny novel roles in tissue remodelling and mucosal immune defences? Dev Comp Immunol. 2018 Jun 14;87:157-170. doi: 10.1016/j.dci.2018.06.006. [Epub ahead of print] PubMed PMID: 29908202. 11: Mahmood NMA, Hussain SA, Khan HAEK. Azilsartan as "Add-On" Treatment with Methotrexate Improves the Disease Activity of Rheumatoid Arthritis. Biomed Res Int. 2018 May 15;2018:7164291. doi: 10.1155/2018/7164291. eCollection 2018. PubMed PMID: 29888275; PubMed Central PMCID: PMC5977001. 12: Dhillon CS, Jakkan MS, Dwivedi R, Medagam NR, Jindal P, Ega S. Outcomes of Unstable Subaxial Cervical Spine Fractures Managed by Posteroanterior Stabilization and Fusion. Asian Spine J. 2018 Jun;12(3):416-422. doi: 10.4184/asj.2018.12.3.416. Epub 2018 Jun 4. PubMed PMID: 29879767; PubMed Central PMCID: PMC6002174. 13: Askie LM, Darlow BA, Finer N, Schmidt B, Stenson B, Tarnow-Mordi W, Davis PG, Carlo WA, Brocklehurst P, Davies LC, Das A, Rich W, Gantz MG, Roberts RS, Whyte RK, Costantini L, Poets C, Asztalos E, Battin M, Halliday HL, Marlow N, Tin W, King A, Juszczak E, Morley CJ, Doyle LW, Gebski V, Hunter KE, Simes RJ; Neonatal Oxygenation Prospective Meta-analysis (NeOProM) Collaboration. Association Between Oxygen Saturation Targeting and Death or Disability in Extremely Preterm Infants in the Neonatal Oxygenation Prospective Meta-analysis Collaboration. JAMA. 2018 Jun 5;319(21):2190-2201. doi: 10.1001/jama.2018.5725. PubMed PMID: 29872859. 14: Salilew-Wondim D, Saeed-Zidane M, Hoelker M, Gebremedhn S, Poirier M, Pandey HO, Tholen E, Neuhoff C, Held E, Besenfelder U, Havlicek V, Rings F, Fournier E, Gagné D, Sirard MA, Robert C, Gad A, Schellander K, Tesfaye D. Genome-wide DNA methylation patterns of bovine blastocysts derived from in vivo embryos subjected to in vitro culture before, during or after embryonic genome activation. BMC Genomics. 2018 Jun 1;19(1):424. doi: 10.1186/s12864-018-4826-3. PubMed PMID: 29859035; PubMed Central PMCID: PMC5984773. 15: Magnadóttir B, Hayes P, Gísladóttir B, Bragason BÞ, Hristova M, Nicholas AP, Guðmundsdóttir S, Lange S. Pentraxins CRP-I and CRP-II are post-translationally deiminated and differ in tissue specificity in cod (Gadus morhua L.) ontogeny. Dev Comp Immunol. 2018 May 17;87:1-11. doi: 10.1016/j.dci.2018.05.014. [Epub ahead of print] PubMed PMID: 29777721. 16: De-Masi A, Davis E, Cuming T, Chindawi N, Pesola F, Cappello C, Chambers S, Bowring J, Rosenthal AN, Sasieni P, Nathan M. The acceptability of high resolution anoscopy examination in patients attending a tertiary referral centre. BMC Cancer. 2018 May 11;18(1):554. doi: 10.1186/s12885-018-4475-6. 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