Phenytoin is an anticonvulsant that is used to treat a wide variety of seizures. It is also an anti-arrhythmic and a muscle relaxant. Phenytoin has been proposed for several other therapeutic uses, but its use has been limited by its many adverse effects and interactions with other drugs.
MedKoo Cat#: 592266
Name: Phenytoin
CAS#: 57-41-0 (free base)
Chemical Formula: C15H12N2O2
Exact Mass: 252.0899
Molecular Weight: 252.27
Elemental Analysis: C, 71.42; H, 4.79; N, 11.10; O, 12.68
Solvent | mg/mL | mM | comments | |
---|---|---|---|---|
Solubility | ||||
DMSO | 41.7 | 165.16 | ||
DMSO:PBS (pH 7.2) (1:1) | 0.5 | 1.98 | ||
Ethanol | 14.0 | 55.50 |
The following data is based on the product molecular weight 252.27 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |