Cycloate | CAS#1134-23-2 | herbicide

MedKoo Cat#: 461021 | Name: Cycloate

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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Cycloate is a herbicide. Cycloate inhibits the biosynthesis of very-long-chain fatty acids, the essential constituents of plant waxes and suberin. Fatty acids also serve as precursors of aliphatic carbon chains in resorcinolic lipids, which play a fundamental role in the plant defence system against fungal pathogens.

Chemical Structure

Cycloate

CAS#1134-23-2

Theoretical Analysis

MedKoo Cat#: 461021

Name: Cycloate

CAS#: 1134-23-2

Chemical Formula: C11H21NOS

Exact Mass: 215.1344

Molecular Weight: 215.35

Elemental Analysis: C, 61.35; H, 9.83; N, 6.50; O, 7.43; S, 14.89

Price and Availability

Size	Price	Availability	Quantity
250mg	USD 350.00	2 Weeks

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Related CAS #

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Synonym

Cycloate; Etsan; R 2063; R-2063; R2063; HSDB 1712; HSDB-1712; HSDB1712;

IUPAC/Chemical Name

S-ethyl cyclohexyl(ethyl)carbamothioate

InChi Key

DFCAFRGABIXSDS-UHFFFAOYSA-N

InChi Code

InChI=1S/C11H21NOS/c1-3-12(11(13)14-4-2)10-8-6-5-7-9-10/h10H,3-9H2,1-2H3

SMILES Code

O=C(SCC)N(C1CCCCC1)CC

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

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Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 215.35 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Czapski J, Horbowicz M, Dobrzanski A, Bakowski J. Residues of cycloate and influence of herbicides on some of nutritional factors in spinach. J Environ Sci Health B. 1983 Aug;18(4-5):497-503. PubMed PMID: 6630897. 2: Magnucka EG, Suzuki Y, Pietr SJ, Kozubek A, Zarnowski R. Cycloate, an inhibitor of fatty acid elongase, modulates the metabolism of very-long-side-chain alkylresorcinols in rye seedlings. Pest Manag Sci. 2009 Oct;65(10):1065-70. doi: 10.1002/ps.1792. PubMed PMID: 19479950. 3: Simpson MG, Horner SA, Mistry P, Duffel S, Widdowson PS, Scanlon Y, Lock EA. Neuropathological studies on cycloate-induced neuronal cell death in the rat brain. Neurotoxicology. 2005 Jan;26(1):125-32. PubMed PMID: 15527880. 4: Abivardi C, Altman J. Effects of cycloate on development of Heterodera schachtii and growth of three Beta species. J Nematol. 1978 Jan;10(1):90-4. PubMed PMID: 19305818; PubMed Central PMCID: PMC2617850. 5: Voronova GF, Aleksandrova LG. [Chromatographic analysis of the herbicide cycloate in the soil]. Gig Sanit. 1989 Aug;(8):46-7. Russian. PubMed PMID: 2591760. 6: Novick NJ, Alexander M. Cometabolism of low concentrations of propachlor, alachlor, and cycloate in sewage and lake water. Appl Environ Microbiol. 1985 Apr;49(4):737-43. PubMed PMID: 4004208; PubMed Central PMCID: PMC238437. 7: Onisko BC, Barnes JP, Staub RE, Walker FH, Kerlinger N. Metabolism of cycloate in radish leaf: metabolite identification by packed capillary flow fast atom bombardment tandem mass spectrometry. Biol Mass Spectrom. 1994 Oct;23(10):626-36. PubMed PMID: 7986833. 8: Aimola IA, Inuwa HM, Nok AJ, Mamman AI, Bieker JJ. Cis-vaccenic acid induces differentiation and up-regulates gamma globin synthesis in K562, JK1 and transgenic mice erythroid progenitor stem cells. Eur J Pharmacol. 2016 Apr 5;776:9-18. doi: 10.1016/j.ejphar.2016.02.041. Epub 2016 Feb 12. PubMed PMID: 26879870; PubMed Central PMCID: PMC5235323. 9: Kosanke GJ, Schwippert WW, Beneke TW. The impairment of mobility and development in freshwater snails (Physa fontinalis and Lymnaea stagnalis) caused by herbicides. Comp Biochem Physiol C. 1988;90(2):373-9. PubMed PMID: 2902998. 10: Hengel M, Lee P. Community air monitoring for pesticides-part 2: multiresidue determination of pesticides in air by gas chromatography, gas chromatography-mass spectrometry, and liquid chromatography-mass spectrometry. Environ Monit Assess. 2014 Mar;186(3):1343-53. doi: 10.1007/s10661-013-3395-9. Epub 2013 Dec 27. PubMed PMID: 24370860. 11: Horowitz M. Herbicidal treatments for control of Papaver somniferum L. Bull Narc. 1980;32(1):33-43. PubMed PMID: 6905769. 12: Suurmeijer TP, Reuvekamp MF, Aldenkamp BP. Social functioning, psychological functioning, and quality of life in epilepsy. Epilepsia. 2001 Sep;42(9):1160-8. PubMed PMID: 11580765. 13: Manenko AK, Gzhegotskiĭ MI, Vidzish AD, Romaniuk LM, Zabrotskiĭ BT. [Hygienic regulation of the intermediate products of the production of ethsane--cyclohexane hydrochloride and ethylcyclohexylamine hydrochloride in various types of bodies of water]. Gig Sanit. 1986 Sep;(9):80-1. Russian. PubMed PMID: 3781284. 14: Kosinkiewicz B, Wegrzyn T, Pietr S. Interaction between bacterial metabolites and some pesticides. II. Change of phytotoxicity of the herbicide Roneet by the phenolic metabolites of Arthrobacter sp. Acta Microbiol Pol. 1984;33(2):111-7. PubMed PMID: 6209927. 15: Quistad GB, Sparks SE, Casida JE. Aldehyde dehydrogenase of mice inhibited by thiocarbamate herbicides. Life Sci. 1994;55(20):1537-44. PubMed PMID: 7968224. 16: Wang Y, Yang WB, Yuan HY, Zhang QX, Zhu XY. [Analysis of the infection status and the drug resistance of mycoplasma and chlamydiae in genitourinary tracts of children with suspected nongonococcal urethritis]. Zhonghua Er Ke Za Zhi. 2009 Jan;47(1):62-4. Chinese. PubMed PMID: 19573386.