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MedKoo Cat#: 597850 | Name: Cgs 25155

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Cgs 25155 is an orally active NEP 24.11 inhibitor.

Chemical Structure

Cgs 25155
Cgs 25155
CAS#150126-87-7

Theoretical Analysis

MedKoo Cat#: 597850

Name: Cgs 25155

CAS#: 150126-87-7

Chemical Formula: C25H34N2O6S

Exact Mass: 490.2138

Molecular Weight: 490.61

Elemental Analysis: C, 61.20; H, 6.99; N, 5.71; O, 19.57; S, 6.53

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Cgs 25155; Cgs-25155; Cgs25155;
IUPAC/Chemical Name
benzyl (2S)-1-((9R)-9-((acetylthio)methyl)-10-oxoazecane-2-carbonyl)-4-hydroxypyrrolidine-2-carboxylate
InChi Key
NGYQCCBRERZOHX-SAZYNNDCSA-N
InChi Code
InChI=1S/C25H34N2O6S/c1-17(28)34-16-19-11-7-2-3-8-12-21(26-23(19)30)24(31)27-14-20(29)13-22(27)25(32)33-15-18-9-5-4-6-10-18/h4-6,9-10,19-22,29H,2-3,7-8,11-16H2,1H3,(H,26,30)/t19-,20?,21?,22-/m0/s1
SMILES Code
O=C(OCC1=CC=CC=C1)[C@H]2N(C(C(CCCCCC[C@H]3CSC(C)=O)NC3=O)=O)CC(O)C2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 490.61 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: MacPherson LJ, Bayburt EK, Capparelli MP, Bohacek RS, Clarke FH, Ghai RD, Sakane Y, Berry CJ, Peppard JV, Trapani AJ. Design and synthesis of an orally active macrocyclic neutral endopeptidase 24.11 inhibitor. J Med Chem. 1993 Nov 26;36(24):3821-8. PubMed PMID: 8254611.