MedKoo Cat#: 592198 | Name: Thiamiprine
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Thiamiprine is an antineoplastic agent.

Chemical Structure

Thiamiprine
Thiamiprine
CAS# 5581-52-2

Theoretical Analysis

MedKoo Cat#: 592198

Name: Thiamiprine

CAS#: 5581-52-2

Chemical Formula: C9H8N8O2S

Exact Mass: 292.0491

Molecular Weight: 292.28

Elemental Analysis: C, 36.99; H, 2.76; N, 38.34; O, 10.95; S, 10.97

Price and Availability

Size Price Availability Quantity
25mg USD 500.00
250mg USD 1,750.00
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Related CAS #
No Data
Synonym
Thiamiprine; NSC-38887; NSC 38887; NSC38887
IUPAC/Chemical Name
1H-Purin-2-amine, 6-((1-methyl-4-nitro-1H-imidazol-5-yl)thio)-
InChi Key
YFTWHEBLORWGNI-UHFFFAOYSA-N
InChi Code
InChI=1S/C9H8N8O2S/c1-16-3-13-6(17(18)19)8(16)20-7-4-5(12-2-11-4)14-9(10)15-7/h2-3H,1H3,(H3,10,11,12,14,15)
SMILES Code
NC1=NC2=NC=NC2=C(SC3=C([N+]([O-])=O)N=CN3C)N1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info
Certificate of Analysis
Safety Data Sheet (SDS)

Preparing Stock Solutions

The following data is based on the product molecular weight 292.28 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Liliemark J, Pettersson B, Lafolie P, Zweig T, Peterson C. Determination of plasma azathioprine and 6-mercaptopurine in patients with rheumatoid arthritis treated with oral azathioprine. Ther Drug Monit. 1990 Jul;12(4):339-43. PubMed PMID: 2396307. 2: Krenitsky TA, Hall WW, Selph JL, Truax JF, Vinegar R. Nucleosides of azathioprine and thiamiprine as antiarthritics. J Med Chem. 1989 Jul;32(7):1471-5. PubMed PMID: 2738881. 3: Filitis LN, Sorkina IuA, Pershin GN, Pevnitskiĭ LA, Solov'ev VV. [Comparative study of toxicity, immunodepressive and tolerogenic activity of thiamiprine, azathioprine and cyclophosphane]. Farmakol Toksikol. 1971 Nov-Dec;34(6):708-13. Russian. PubMed PMID: 5139795.