MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 563277 | Name: FCPT

Description:

WARNING: This product is for research use only, not for human or veterinary use.

FCPT is an ATP competitive inhibitor of kinesin-5.

Chemical Structure

FCPT
FCPT
CAS#862250-23-5

Theoretical Analysis

MedKoo Cat#: 563277

Name: FCPT

CAS#: 862250-23-5

Chemical Formula: C17H13FN2S

Exact Mass: 296.0783

Molecular Weight: 296.36

Elemental Analysis: C, 68.90; H, 4.42; F, 6.41; N, 9.45; S, 10.82

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
FCPT;
IUPAC/Chemical Name
2-(1-(4-Fluorophenyl)cyclopropyl)-4-(pyridin-4-yl)thiazole
InChi Key
PVPYZVCHGWNKFZ-UHFFFAOYSA-N
InChi Code
InChI=1S/C17H13FN2S/c18-14-3-1-13(2-4-14)17(7-8-17)16-20-15(11-21-16)12-5-9-19-10-6-12/h1-6,9-11H,7-8H2
SMILES Code
FC1=CC=C(C2(C3=NC(C4=CC=NC=C4)=CS3)CC2)C=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 296.36 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Hattenbach LO, Feltgen N, Bertelmann T, Schmitz-Valckenberg S, Berk H, Eter N, Lang GE, Rehak M, Taylor SR, Wolf A, Weiss C, Paulus EM, Pielen A, Hoerauf H; COMRADE-B Study Group. Head-to-head comparison of ranibizumab PRN versus single-dose dexamethasone for branch retinal vein occlusion (COMRADE-B). Acta Ophthalmol. 2018 Feb;96(1):e10-e18. doi: 10.1111/aos.13381. Epub 2017 Mar 2. PubMed PMID: 28251811. 2: Dyakova ME. Features purine metabolism in patients with pulmonary tuberculosis. Patol Fiziol Eksp Ter. 2016 Jul-Sep;60(3):36-41. PubMed PMID: 29244467. 3: Dong N, Xu B, Wang B, Chu L, Tang X. Aqueous cytokines as predictors of macular edema in patients with diabetes following uncomplicated phacoemulsification cataract surgery. Biomed Res Int. 2015;2015:126984. doi: 10.1155/2015/126984. Epub 2015 Feb 25. PubMed PMID: 25811020; PubMed Central PMCID: PMC4355626. 4: Alm S, Olsen SO, Honkanen P. The role of family communication and parents' feeding practices in children's food preferences. Appetite. 2015 Jun;89:112-21. doi: 10.1016/j.appet.2015.02.002. Epub 2015 Feb 7. PubMed PMID: 25666300. 5: Chu L, Wang B, Xu B, Dong N. Aqueous cytokines as predictors of macular edema in non-diabetic patients following uncomplicated phacoemulsification cataract surgery. Mol Vis. 2013 Nov 24;19:2418-25. eCollection 2013. PubMed PMID: 24319335; PubMed Central PMCID: PMC3850971. 6: Collins E, Mann BJ, Wadsworth P. Eg5 restricts anaphase B spindle elongation in mammalian cells. Cytoskeleton (Hoboken). 2014 Feb;71(2):136-44. doi: 10.1002/cm.21158. Epub 2013 Dec 12. PubMed PMID: 24285623; PubMed Central PMCID: PMC5397254. 7: Titarenko OT, D'iakova ME, Ésmedliaeva DS, Pavlova MV, El'kin AV, Alekseeva NP, Bondarenko BB. [Peculiarities of the circulating phagocytes functional activity in patients with different forms of drug-resistant pulmonary tuberculosis]. Biomed Khim. 2012 Jul-Aug;58(4):467-74. Russian. PubMed PMID: 23413691. 8: Hommer A. [Combination therapy in the medical treatment of glaucoma]. Klin Monbl Augenheilkd. 2013 Feb;230(2):133-40. doi: 10.1055/s-0032-1328095. Epub 2013 Jan 20. German. PubMed PMID: 23335083. 9: Groen AC, Needleman D, Brangwynne C, Gradinaru C, Fowler B, Mazitschek R, Mitchison TJ. A novel small-molecule inhibitor reveals a possible role of kinesin-5 in anastral spindle-pole assembly. J Cell Sci. 2008 Jul 15;121(Pt 14):2293-300. doi: 10.1242/jcs.024018. Epub 2008 Jun 17. PubMed PMID: 18559893; PubMed Central PMCID: PMC2902979. 10: Shmelev EI, Kuklina GM, Kalinina EE. [Treatment of bronchial obstruction in patients with pulmonary tuberculosis]. Probl Tuberk Bolezn Legk. 2004;(8):57-61. Russian. PubMed PMID: 15478563. 11: Erokhin VV, Gedymin LE, Zemskova S, Lepekha LN, Podolianko PN. [Features of morphological reactions in caseous pneumonia]. Probl Tuberk. 2001;(7):50-5. Russian. PubMed PMID: 11763566. 12: Kakizoe S, Kakizoe Y, Kakizoe S. [Frequent chemolipiodolization and prostaglandin E1 administration for hepatocellular carcinoma with advanced liver cirrhosis]. Nihon Shokakibyo Gakkai Zasshi. 1998 Apr;95(4):311-6. Japanese. PubMed PMID: 9591406.