7ETMC is a selective Inhibitor of Human Cytochrome P450s 1A1 and 1A2. 7ETMC showed IC(50) values of 0.46 μM and 0.50 μM for P450s 1A1 and 1A2 in the first six minutes, respectively, and did not show any inhibition activity for P450s 2A6 and 2B1 even at the dose of 50 μM.
MedKoo Cat#: 558392
Name: 7ETMC
CAS#: 1370702-83-2
Chemical Formula: C14H12O2
Exact Mass: 212.0800
Molecular Weight: 212.25
Elemental Analysis: C, 79.23; H, 5.70; O, 15.08
The following data is based on the product molecular weight 212.25 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
