Penniclavine is an ergot alkaloid produced by certain Claviceps species, often found in contaminated cereal grains. It acts as a partial agonist or antagonist at various neurotransmitter receptors, particularly serotonin and dopamine receptors, affecting smooth muscle contraction and vascular tone. While not commonly used directly in medicine, penniclavine serves as a reference compound in pharmacological research on ergot alkaloid activity. Its mechanism involves mimicking neurotransmitters, thereby influencing nervous system and vascular responses.
MedKoo Cat#: 146296
Name: Penniclavine
CAS#: 519-13-1
Chemical Formula: C16H18N2O2
Exact Mass: 270.1368
Molecular Weight: 270.33
Elemental Analysis: C, 71.09; H, 6.71; N, 10.36; O, 11.84
The following data is based on the product molecular weight 270.33 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
