Endrin | CAS#72-20-8 | biochemical

MedKoo Cat#: 592068 | Name: Endrin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Endrin is found in food products.

Chemical Structure

Endrin

CAS#72-20-8

Theoretical Analysis

MedKoo Cat#: 592068

Name: Endrin

CAS#: 72-20-8

Chemical Formula: C12H8CL6O

Exact Mass: 377.8706

Molecular Weight: 377.90

Elemental Analysis: C, 37.84; H, 2.12; Cl, 55.84; O, 4.20

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Related CAS #

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Synonym

Endrin; NSC 8935; NSC-8935; NSC8935

IUPAC/Chemical Name

1,4:5,8-Dimethanonaphthalene, 1,2,3,4,10,10-hexachloro-6,7-epoxy-1,4,4a,5,6,7,8,8a-octahydro-, endo,endo-

InChi Key

DFBKLUNHFCTMDC-UHFFFAOYSA-N

InChi Code

InChI=1S/C12H8Cl6O/c13-8-9(14)11(16)5-3-1-2(6-7(3)19-6)4(5)10(8,15)12(11,17)18/h2-7H,1H2

SMILES Code

ClC1(Cl)C2(Cl)C(Cl)=C(Cl)C1(Cl)C3C(C4)C(O5)C5C4C23

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 377.90 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Rahman MM, Lee HS, Abd El-Aty AM, Kabir MH, Chung HS, Park JH, Kim MR, Kim JH, Shin HC, Shin SS, Shim JH. Determination of endrin and δ-keto endrin in five food products of animal origin using GC-μECD: A modified QuEChERS approach to traditional detection. Food Chem. 2018 Oct 15;263:59-66. doi: 10.1016/j.foodchem.2018.04.099. Epub 2018 Apr 27. PubMed PMID: 29784328. 2: Abbasi Y, Mannaerts CM. Evaluating organochlorine pesticide residues in the aquatic environment of the Lake Naivasha River basin using passive sampling techniques. Environ Monit Assess. 2018 May 18;190(6):349. doi: 10.1007/s10661-018-6713-4. PubMed PMID: 29777312; PubMed Central PMCID: PMC5959953. 3: Ruiz-Toledo J, Vandame R, Castro-Chan RA, Penilla-Navarro RP, Gómez J, Sánchez D. Organochlorine Pesticides in Honey and Pollen Samples from Managed Colonies of the Honey Bee Apis mellifera Linnaeus and the Stingless Bee Scaptotrigona mexicana Guérin from Southern, Mexico. Insects. 2018 May 10;9(2). pii: E54. doi: 10.3390/insects9020054. PubMed PMID: 29748485; PubMed Central PMCID: PMC6023274. 4: Navarrete IA, Tee KAM, Unson JRS, Hallare AV. Organochlorine pesticide residues in surface water and groundwater along Pampanga River, Philippines. Environ Monit Assess. 2018 Apr 17;190(5):289. doi: 10.1007/s10661-018-6680-9. PubMed PMID: 29667072. 5: Affum AO, Acquaah SO, Osae SD, Kwaansa-Ansah EE. Distribution and risk assessment of banned and other current-use pesticides in surface and groundwaters consumed in an agricultural catchment dominated by cocoa crops in the Ankobra Basin, Ghana. Sci Total Environ. 2018 Aug 15;633:630-640. doi: 10.1016/j.scitotenv.2018.03.129. Epub 2018 Mar 28. PubMed PMID: 29597160. 6: Ogbeide O, Chukwuka A, Tongo I, Ezemonye L. Relationship between geosorbent properties and field-based partition coefficients for pesticides in surface water and sediments of selected agrarian catchments: Implications for risk assessment. J Environ Manage. 2018 Jul 1;217:23-37. doi: 10.1016/j.jenvman.2018.03.065. Epub 2018 Mar 24. PubMed PMID: 29579538. 7: Wrobel MH, Mlynarczuk J. Chlorinated insecticides (toxaphene and endrin) affect oxytocin, testosterone, oestradiol and prostaglandin secretion from ovarian and uterine cells as well as myometrial contractions in cow in vitro. Chemosphere. 2018 May;198:432-441. doi: 10.1016/j.chemosphere.2018.01.143. Epub 2018 Feb 3. PubMed PMID: 29425943. 8: Chang GR. Persistent organochlorine pesticides in aquatic environments and fishes in Taiwan and their risk assessment. Environ Sci Pollut Res Int. 2018 Mar;25(8):7699-7708. doi: 10.1007/s11356-017-1110-z. Epub 2017 Dec 29. PubMed PMID: 29288298. 9: Tankiewicz M, Biziuk M. Fast, sensitive and reliable multi-residue method for routine determination of 34 pesticides from various chemical groups in water samples by using dispersive liquid-liquid microextraction coupled with gas chromatography-mass spectrometry. Anal Bioanal Chem. 2018 Feb;410(5):1533-1550. doi: 10.1007/s00216-017-0798-4. Epub 2017 Dec 18. PubMed PMID: 29256082. 10: Rivas-Hernández G, May-Uc Y, Noreña-Barroso E, Cobos-Gasca V, Rodríguez-Fuentes G. Plasma Cholinesterase Activity in Female Green Turtles Chelonia mydas Nesting in Laguna de Terminos, Mexico Related to Organochlorine Pesticides in Their Eggs. Bull Environ Contam Toxicol. 2018 Jan;100(1):101-105. doi: 10.1007/s00128-017-2250-z. Epub 2017 Dec 14. PubMed PMID: 29243208. 11: Witczak A, Abdel-Gawad H, Zalesak M, Pohoryło A. Tracking residual organochlorine pesticides (OCPs) in green, herbal, and black tea leaves and infusions of commercially available tea products marketed in Poland. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2018 Mar;35(3):479-486. doi: 10.1080/19440049.2017.1411614. Epub 2017 Dec 28. PubMed PMID: 29210611. 12: Unyimadu JP, Osibanjo O, Babayemi JO. Selected persistent organic pollutants (POPs) in water of River Niger: occurrence and distribution. Environ Monit Assess. 2017 Dec 6;190(1):6. doi: 10.1007/s10661-017-6378-4. PubMed PMID: 29209805. 13: Baqar M, Sadef Y, Ahmad SR, Mahmood A, Li J, Zhang G. Organochlorine pesticides across the tributaries of River Ravi, Pakistan: Human health risk assessment through dermal exposure, ecological risks, source fingerprints and spatio-temporal distribution. Sci Total Environ. 2018 Mar 15;618:291-305. doi: 10.1016/j.scitotenv.2017.10.234. Epub 2017 Nov 10. PubMed PMID: 29131997. 14: Sharip Z, Hashim N, Suratman S. Occurrence of organochlorine pesticides in a tropical lake basin. Environ Monit Assess. 2017 Oct 15;189(11):560. doi: 10.1007/s10661-017-6274-y. PubMed PMID: 29034408. 15: do Carmo SN, Merib J, Dias AN, Stolberg J, Budziak D, Carasek E. A low-cost biosorbent-based coating for the highly sensitive determination of organochlorine pesticides by solid-phase microextraction and gas chromatography-electron capture detection. J Chromatogr A. 2017 Nov 24;1525:23-31. doi: 10.1016/j.chroma.2017.10.018. Epub 2017 Oct 7. PubMed PMID: 29030033. 16: Qu C, Albanese S, Lima A, Li J, Doherty AL, Qi S, De Vivo B. Residues of hexachlorobenzene and chlorinated cyclodiene pesticides in the soils of the Campanian Plain, southern Italy. Environ Pollut. 2017 Dec;231(Pt 2):1497-1506. doi: 10.1016/j.envpol.2017.08.100. Epub 2017 Sep 28. PubMed PMID: 28964601. 17: Oyekunle JAO, Akindolani OA, Sosan MB, Adekunle AS. Organochlorine pesticide residues in dried cocoa beans obtained from cocoa stores at Ondo and Ile-Ife, Southwestern Nigeria. Toxicol Rep. 2017 Mar 6;4:151-159. doi: 10.1016/j.toxrep.2017.03.001. eCollection 2017. PubMed PMID: 28959635; PubMed Central PMCID: PMC5615113. 18: Ben Salem F, Ben Said O, Mahmoudi E, Duran R, Monperrus M. Distribution of organic contamination of sediments from Ichkeul Lake and Bizerte Lagoon, Tunisia. Mar Pollut Bull. 2017 Oct 15;123(1-2):329-338. doi: 10.1016/j.marpolbul.2017.09.024. Epub 2017 Sep 14. PubMed PMID: 28918983. 19: Shrivas K, Ghosale A, Nirmalkar N, Srivastava A, Singh SK, Shinde SS. Removal of endrin and dieldrin isomeric pesticides through stereoselective adsorption behavior on the graphene oxide-magnetic nanoparticles. Environ Sci Pollut Res Int. 2017 Nov;24(32):24980-24988. doi: 10.1007/s11356-017-0159-z. Epub 2017 Sep 16. PubMed PMID: 28918582. 20: Abd El-Moneam NM, Shreadah MA, El-Assar SA, Nabil-Adam A. Protective role of antioxidants capacity of Hyrtios aff. Erectus sponge extract against mixture of persistent organic pollutants (POPs)-induced hepatic toxicity in mice liver: biomarkers and ultrastructural study. Environ Sci Pollut Res Int. 2017 Sep;24(27):22061-22072. doi: 10.1007/s11356-017-9805-8. Epub 2017 Aug 8. PubMed PMID: 28791578.