MedKoo Cat#: 592027 | Name: O-Methylsalicylic acid
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

O-Methylsalicylic acid is a novel antiemetic which prevents nausea and vomiting in humans. Its actions are unclear but most likely involves the chemoreceptor trigger zone (CTZ)

Chemical Structure

O-Methylsalicylic acid
O-Methylsalicylic acid
CAS# 579-75-9

Theoretical Analysis

MedKoo Cat#: 592027

Name: O-Methylsalicylic acid

CAS#: 579-75-9

Chemical Formula: C8H8O3

Exact Mass: 152.0473

Molecular Weight: 152.15

Elemental Analysis: C, 63.15; H, 5.30; O, 31.55

Price and Availability

Size Price Availability Quantity
25g USD 220.00
100g USD 350.00
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Related CAS #
No Data
Synonym
O-Methylsalicylic acid; NSC 3778; NSC-3778; NSC3778
IUPAC/Chemical Name
Benzoic acid, 2-methoxy-
InChi Key
ILUJQPXNXACGAN-UHFFFAOYSA-N
InChi Code
InChI=1S/C8H8O3/c1-11-7-5-3-2-4-6(7)8(9)10/h2-5H,1H3,(H,9,10)
SMILES Code
O=C(O)C1=CC=CC=C1OC
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info
Product Data
Biological target:
O-Methylsalicylic acid is a novel antiemetic which prevents nausea and vomiting in humans.
In vitro activity:
TBD
In vivo activity:
TBD
Solvent mg/mL mM
Solubility
DMSO 65.0 427.21
Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 152.15 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
TBD
In vitro protocol:
TBD
In vivo protocol:
TBD
1: Zhu DX, Zhao JL, Mo L, Li HL. Drug allergy: identification and characterization of IgE-reactivities to aspirin and related compounds. J Investig Allergol Clin Immunol. 1997 May-Jun;7(3):160-8. PubMed PMID: 9252874.