Synonym
Dansylleucine; Dns-leucine; Dansyl-leucine; Dns-Leu-OH; Dansyl-L-leucine
IUPAC/Chemical Name
((5-(dimethylamino)naphthalen-1-yl)sulfonyl)-L-leucine
InChi Key
XBMQRPDOXIPUFG-HNNXBMFYSA-N
InChi Code
InChI=1S/C18H24N2O4S/c1-12(2)11-15(18(21)22)19-25(23,24)17-10-6-7-13-14(17)8-5-9-16(13)20(3)4/h5-10,12,15,19H,11H2,1-4H3,(H,21,22)/t15-/m0/s1
SMILES Code
CC(C)C[C@@H](C(O)=O)NS(=O)(C1=C2C=CC=C(N(C)C)C2=CC=C1)=O
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
Preparing Stock Solutions
The following data is based on the
product
molecular weight
364.46
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
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2: Li Z, Hu C, Liu Y, Li Q, Fu Y, Chen Z. Facile preparation of ethanediamine-β- cyclodextrin modified capillary column for electrochromatographic enantioseparation of Dansyl amino acids. J Chromatogr A. 2021 Apr 26;1643:462082. doi: 10.1016/j.chroma.2021.462082. Epub 2021 Mar 18. PMID: 33780884.
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6: Atamna IZ, Issaq HJ, Muschik GM, Janini GM. Optimization of resolution in capillary zone electrophoresis: combined effect of applied voltage and buffer concentration. J Chromatogr. 1991 Dec 27;588(1-2):315-20. doi: 10.1016/0021-9673(91)85039-i. PMID: 1818085.
7: Yin D, Xie C, Zhang L, Liu B, Zhou X, Wang P, Wu M. Development of a novel capillary electrophoresis chemiluminescence system for amino acid analysis. Luminescence. 2008 Nov-Dec;23(6):434-8. doi: 10.1002/bio.1076. PMID: 18800361.
8: Tamura A, Khademizadeh M, Tamura K, Masujima T. Direct observation of the separation process by the chromato-videoscope. J Pharm Biomed Anal. 1997 Jun;15(9-10):1477-82. doi: 10.1016/s0731-7085(97)00018-6. PMID: 9226578.
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