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MedKoo Cat#: 591971 | Name: Dibenzylamine
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Dibenzylamine is an organic compound with a secondary amine functional group, known for its role as a chemical intermediate in pharmaceutical and agrochemical synthesis. Its mechanism of action varies depending on its derivative; certain dibenzylamine-based compounds exhibit bioactivity as calcium channel blockers, influencing vascular smooth muscle relaxation and potential antihypertensive effects. Additionally, dibenzylamine derivatives have been investigated for their antimicrobial and antifungal properties, with applications in the development of therapeutic agents targeting infectious diseases.

Chemical Structure

Dibenzylamine
Dibenzylamine
CAS#103-49-1

Theoretical Analysis

MedKoo Cat#: 591971

Name: Dibenzylamine

CAS#: 103-49-1

Chemical Formula: C14H15N

Exact Mass: 197.1204

Molecular Weight: 197.28

Elemental Analysis: C, 85.24; H, 7.66; N, 7.10

Price and Availability

Size Price Availability Quantity
25g USD 250.00 2 Weeks
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Related CAS #
No Data
Synonym
Dibenzylamine; N-Benzylbenzylamine; N,N-Dibenylamine; N,N-Dibenzylamine; NSC-4811; NSC4811; NSC 4811;
IUPAC/Chemical Name
Benzenemethanamine, N-(phenylmethyl)-
InChi Key
BWLUMTFWVZZZND-UHFFFAOYSA-N
InChi Code
InChI=1S/C14H15N/c1-3-7-13(8-4-1)11-15-12-14-9-5-2-6-10-14/h1-10,15H,11-12H2
SMILES Code
C1(CNCC2=CC=CC=C2)=CC=CC=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 197.28 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
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J Inorg Biochem. 2017 Jul;172:9-15. doi: 10.1016/j.jinorgbio.2017.04.004. Epub 2017 Apr 4. PubMed PMID: 28414928. 5: Shi Y, Noelle DJ, Wang M, Le AV, Yoon H, Zhang M, Meng YS, Qiao Y. Role of Amines in Thermal-Runaway-Mitigating Lithium-Ion Battery. ACS Appl Mater Interfaces. 2016 Nov 16;8(45):30956-30963. Epub 2016 Nov 3. PubMed PMID: 27786445. 6: Deng W, Chen J, Kang J, Zhang Q, Wang Y. Carbon nanotube-supported Au-Pd alloy with cooperative effect of metal nanoparticles and organic ketone/quinone groups as a highly efficient catalyst for aerobic oxidation of amines. Chem Commun (Camb). 2016 May 21;52(41):6805-8. doi: 10.1039/c6cc01490a. Epub 2016 Apr 29. PubMed PMID: 27125360. 7: Inci Gul H, Yamali C, Tugce Yasa A, Unluer E, Sakagami H, Tanc M, Supuran CT. Carbonic anhydrase inhibition and cytotoxicity studies of Mannich base derivatives of thymol. J Enzyme Inhib Med Chem. 2016 Dec;31(6):1375-80. doi: 10.3109/14756366.2016.1140755. Epub 2016 Feb 5. PubMed PMID: 26850788. 8: Shi JL, Li FB, Zhang XF, Wu J, Zhang HY, Peng J, Liu CX, Liu L, Wu P, Li JX. Synthesis and Functionalization of Symmetrical 2,5-Diaryl Fulleropyrrolidines: Ferric Perchlorate-Mediated One-Step Reaction of [60]Fullerene with Arylmethanamines. J Org Chem. 2016 Mar 4;81(5):1769-77. doi: 10.1021/acs.joc.5b02412. Epub 2016 Feb 18. PubMed PMID: 26841702. 9: Inokuchi Y, Haino T, Sekiya R, Morishima F, Dedonder C, Féraud G, Jouvet C, Ebata T. UV photodissociation spectroscopy of cryogenically cooled gas phase host-guest complex ions of crown ethers. Phys Chem Chem Phys. 2015 Oct 21;17(39):25925-34. doi: 10.1039/c5cp01960e. PubMed PMID: 26095662. 10: Kim S, Ginsbach JW, Lee JY, Peterson RL, Liu JJ, Siegler MA, Sarjeant AA, Solomon EI, Karlin KD. Amine oxidative N-dealkylation via cupric hydroperoxide Cu-OOH homolytic cleavage followed by site-specific fenton chemistry. J Am Chem Soc. 2015 Mar 4;137(8):2867-74. doi: 10.1021/ja508371q. Epub 2015 Feb 23. PubMed PMID: 25706825; PubMed Central PMCID: PMC4482616. 11: Szakonyi Z, Sillanpää R, Fülöp F. Stereoselective synthesis of perillaldehyde-based chiral β-amino acid derivatives through conjugate addition of lithium amides. Beilstein J Org Chem. 2014 Nov 21;10:2738-42. doi: 10.3762/bjoc.10.289. eCollection 2014. PubMed PMID: 25550738; PubMed Central PMCID: PMC4273274. 12: Nagae H, Shibata Y, Tsurugi H, Mashima K. Aminomethylation reaction of ortho-pyridyl C-H bonds catalyzed by group 3 metal triamido complexes. J Am Chem Soc. 2015 Jan 21;137(2):640-3. doi: 10.1021/ja511964k. Epub 2015 Jan 5. PubMed PMID: 25543453. 13: Deshmukh SC, Talukdar P. Stereoselective synthesis of (2S,3R)-α-hydroxy-β-amino acids (AHBAs): valinoctin A, (2S,3R)-3-amino-2-hydroxydecanoic acid, and a fluorescent-labeled (2S,3R)-AHBA. J Org Chem. 2014 Nov 21;79(22):11215-25. doi: 10.1021/jo501751u. Epub 2014 Oct 31. PubMed PMID: 25308171. 14: Shao G, Chen G, Zuo J, Gong M, Yang Q. Organometallic synthesis, structure determination, shape evolution, and formation mechanism of hexapod-like ternary PbSe(x)S(1-x) nanostructures with tunable compositions. Langmuir. 2014 Jul 8;30(26):7811-22. doi: 10.1021/la501267f. Epub 2014 Jun 25. PubMed PMID: 24963993. 15: Davies SG, Fletcher AM, Foster EM, Houlsby IT, Roberts PM, Schofield TM, Thomson JE. An efficient asymmetric synthesis of (-)-lupinine. Chem Commun (Camb). 2014 Aug 7;50(61):8309-11. doi: 10.1039/c4cc02135e. PubMed PMID: 24938152. 16: Pavlenko NV, Oos TI, Yagupolskii YL, Gerus II, Doeller U, Willms L. A novel family of (1-aminoalkyl)(trifluoromethyl)- and -(difluoromethyl)phosphinic acids - analogues of α-amino acids. Beilstein J Org Chem. 2014 Mar 26;10:722-31. doi: 10.3762/bjoc.10.66. eCollection 2014. PubMed PMID: 24778725; PubMed Central PMCID: PMC3999843. 17: Dsikowitzky L, Nordhaus I, Sujatha CH, Akhil PS, Soman K, Schwarzbauer J. A combined chemical and biological assessment of industrial contamination in an estuarine system in Kerala, India. Sci Total Environ. 2014 Jul 1;485-486:348-362. doi: 10.1016/j.scitotenv.2014.03.034. Epub 2014 Apr 14. PubMed PMID: 24735943. 18: Féraud G, Dedonder C, Jouvet C, Inokuchi Y, Haino T, Sekiya R, Ebata T. Development of Ultraviolet-Ultraviolet Hole-Burning Spectroscopy for Cold Gas-Phase Ions. J Phys Chem Lett. 2014 Apr 3;5(7):1236-40. doi: 10.1021/jz500478w. Epub 2014 Mar 24. PubMed PMID: 26274477. 19: Abbaz T, Bendjeddou A, Gouasmia A, Villemin D, Shirahata T. New unsymmetrically benzene-fused bis (tetrathiafulvalene): synthesis, characterization, electrochemical properties and electrical conductivity of their materials. Int J Mol Sci. 2014 Mar 17;15(3):4550-64. doi: 10.3390/ijms15034550. PubMed PMID: 24642878; PubMed Central PMCID: PMC3975413. 20: Shao G, Chen G, Yang W, Ding T, Zuo J, Yang Q. Organometallic-route synthesis, controllable growth, mechanism investigation, and surface feature of PbSe nanostructures with tunable shapes. Langmuir. 2014 Mar 18;30(10):2863-72. doi: 10.1021/la4042869. Epub 2014 Mar 7. PubMed PMID: 24559144.

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