F-991 | CAS#188193-59-1 | peptide inhibitor

MedKoo Cat#: 597435 | Name: F-991

Description:

WARNING: This product is for research use only, not for human or veterinary use.

F-991 is a peptide inhibitor that has demonstrated remarkable biological activity in a number of animal models of allergic diseases, and promise for the potential treatment of allergic diseases in humans.

Chemical Structure

F-991

CAS#188193-59-1

Theoretical Analysis

MedKoo Cat#: 597435

Name: F-991

CAS#: 188193-59-1

Chemical Formula: C43H60N14O11S2

Exact Mass: 1012.4007

Molecular Weight: 1013.16

Elemental Analysis: C, 50.98; H, 5.97; N, 19.36; O, 17.37; S, 6.33

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

F-991; F 991; F991; Ala-his-trp-ser-gly-his-cys-cys-leu;

IUPAC/Chemical Name

L-alanyl-L-histidyl-L-tryptophyl-L-serylglycyl-L-histidyl-L-cysteinyl-L-cysteinyl-L-leucine

InChi Key

BWCARSGBKSFOCL-OSTURJEUSA-N

InChi Code

InChI=1S/C43H60N14O11S2/c1-21(2)8-31(43(67)68)54-41(65)33(17-69)57-42(66)34(18-70)56-39(63)29(10-24-13-45-19-49-24)51-35(59)15-48-37(61)32(16-58)55-38(62)28(9-23-12-47-27-7-5-4-6-26(23)27)53-40(64)30(52-36(60)22(3)44)11-25-14-46-20-50-25/h4-7,12-14,19-22,28-34,47,58,69-70H,8-11,15-18,44H2,1-3H3,(H,45,49)(H,46,50)(H,48,61)(H,51,59)(H,52,60)(H,53,64)(H,54,65)(H,55,62)(H,56,63)(H,57,66)(H,67,68)/t22-,28-,29-,30-,31-,32-,33-,34-/m0/s1

SMILES Code

CC(C)C[C@@H](C(O)=O)NC([C@H](CS)NC([C@H](CS)NC([C@H](CC1=CNC=N1)NC(CNC([C@H](CO)NC([C@H](CC2=CNC3=C2C=CC=C3)NC([C@H](CC4=CNC=N4)NC([C@H](C)N)=O)=O)=O)=O)=O)=O)=O)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 1,013.16 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Redegeld FA, Wortel CH. IgE and immunoglobulin free light chains in allergic disease: new therapeutic opportunities. Curr Opin Investig Drugs. 2008 Nov;9(11):1185-91. Review. PubMed PMID: 18951298.