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MedKoo Cat#: 591959 | Name: Chlordene
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Chlordene is a chlorinated hydrocarbon compound that was historically used as an intermediate in the synthesis of the pesticide chlordane. Structurally, it is a polycyclic organochlorine with high environmental persistence and potential for bioaccumulation. While not widely used on its own, it shares the toxicological concerns associated with related organochlorines, including possible neurotoxic and endocrine-disrupting effects.

Chemical Structure

Chlordene
Chlordene
CAS#3734-48-3

Theoretical Analysis

MedKoo Cat#: 591959

Name: Chlordene

CAS#: 3734-48-3

Chemical Formula: C10H6Cl6

Exact Mass: 335.8601

Molecular Weight: 335.86

Elemental Analysis: C, 35.45; H, 1.78; Cl, 62.77

Price and Availability

Size Price Availability Quantity
50mg USD 250.00 2 Weeks
100mg USD 450.00 2 Weeks
250mg USD 850.00 2 Weeks
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Related CAS #
No Data
Synonym
Chlordene; AI3-15150; AI3 15150; AI315150
IUPAC/Chemical Name
4,5,6,7,8,8-Hexachloro-3a,4,7,7a-tetrahydro-4,7-methano-1H-indene
InChi Key
XCJXQCUJXDUNDN-UHFFFAOYSA-N
InChi Code
InChI=1S/C10H6Cl6/c11-6-7(12)9(14)5-3-1-2-4(5)8(6,13)10(9,15)16/h1-2,4-5H,3H2
SMILES Code
ClC1(Cl)C2(Cl)C3C=CCC3C1(Cl)C(Cl)=C2Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 335.86 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Abdel Malak I, Cariou R, Vénisseau A, Dervilly-Pinel G, Jaber F, Babut M, Le Bizec B. Occurrence of Dechlorane Plus and related compounds in catfish (Silurus spp.) from rivers in France. Chemosphere. 2018 Sep;207:413-420. doi: 10.1016/j.chemosphere.2018.05.101. Epub 2018 May 20. PubMed PMID: 29803891. 2: Simond AE, Houde M, Lesage V, Verreault J. Temporal trends of PBDEs and emerging flame retardants in belugas from the St. Lawrence Estuary (Canada) and comparisons with minke whales and Canadian Arctic belugas. Environ Res. 2017 Jul;156:494-504. doi: 10.1016/j.envres.2017.03.058. Epub 2017 Apr 26. PubMed PMID: 28419962. 3: Gallistl C, Lok B, Schlienz A, Vetter W. Polyhalogenated compounds (chlorinated paraffins, novel and classic flame retardants, POPs) in dishcloths after their regular use in households. Sci Total Environ. 2017 Oct 1;595:303-314. doi: 10.1016/j.scitotenv.2017.03.217. Epub 2017 Apr 4. PubMed PMID: 28384585. 4: Brasseur C, Pirard C, L'homme B, De Pauw E, Focant JF. Measurement of Emerging Dechloranes in Human Serum Using Modulated Gas Chromatography Coupled to Electron Capture Negative Ionization Time-of-Flight Mass Spectrometry. Rapid Commun Mass Spectrom. 2016 Sep 21. doi: 10.1002/rcm.7745. [Epub ahead of print] PubMed PMID: 27654949. 5: L'Homme B, Calaprice C, Calvano CD, Zambonin C, Leardi R, Focant JF. Ultra-trace measurement of Dechloranes to investigate food as a route of human exposure. Chemosphere. 2015 Nov;139:525-33. doi: 10.1016/j.chemosphere.2015.07.043. Epub 2015 Aug 24. PubMed PMID: 26313934. 6: Wang DG, Guo MX, Pei W, Byer JD, Wang Z. Trophic magnification of chlorinated flame retardants and their dechlorinated analogs in a fresh water food web. Chemosphere. 2015 Jan;118:293-300. PubMed PMID: 25463253. 7: Purnomo AS, Putra SR, Shimizu K, Kondo R. Biodegradation of heptachlor and heptachlor epoxide-contaminated soils by white-rot fungal inocula. Environ Sci Pollut Res Int. 2014 Oct;21(19):11305-12. doi: 10.1007/s11356-014-3026-1. Epub 2014 May 20. PubMed PMID: 24840358. 8: Houde M, Berryman D, de Lafontaine Y, Verreault J. Novel brominated flame retardants and dechloranes in three fish species from the St. Lawrence River, Canada. Sci Total Environ. 2014 May 1;479-480:48-56. doi: 10.1016/j.scitotenv.2014.01.105. Epub 2014 Feb 15. PubMed PMID: 24534698. 9: Brasseur C, Pirard C, Scholl G, De Pauw E, Viel JF, Shen L, Reiner EJ, Focant JF. Levels of dechloranes and polybrominated diphenyl ethers (PBDEs) in human serum from France. Environ Int. 2014 Apr;65:33-40. doi: 10.1016/j.envint.2013.12.014. Epub 2014 Jan 15. PubMed PMID: 24440800. 10: de la Torre A, Alonso MB, Martínez MA, Sanz P, Shen L, Reiner EJ, Lailson-Brito J, Torres JP, Bertozzi C, Marigo J, Barbosa L, Cremer M, Secchi E, Malm O, Eljarrat E, Barceló D. Dechlorane-related compounds in franciscana dolphin (Pontoporia blainvillei) from southeastern and southern coast of Brazil. Environ Sci Technol. 2012 Nov 20;46(22):12364-72. doi: 10.1021/es302934p. Epub 2012 Oct 12. PubMed PMID: 23016984. 11: Xiao P, Mori T, Kondo R. Biotransformation of the organochlorine pesticide trans-chlordane by wood-rot fungi. N Biotechnol. 2011 Dec 15;29(1):107-15. doi: 10.1016/j.nbt.2011.06.013. Epub 2011 Jun 28. PubMed PMID: 21718811. 12: Shen L, Reiner EJ, Helm PA, Marvin CH, Hill B, Zhang X, Macpherson KA, Kolic TM, Tomy GT, Brindle ID. Historic trends of dechloranes 602, 603, 604, dechlorane plus and other norbornene derivatives and their bioaccumulation potential in lake ontario. Environ Sci Technol. 2011 Apr 15;45(8):3333-40. doi: 10.1021/es104328r. Epub 2011 Mar 24. PubMed PMID: 21434636. 13: Shen L, Reiner EJ, MacPherson KA, Kolic TM, Helm PA, Richman LA, Marvin CH, Burniston DA, Hill B, Brindle ID, McCrindle R, Chittim BG. Dechloranes 602, 603, 604, Dechlorane Plus, and Chlordene Plus, a newly detected analogue, in tributary sediments of the Laurentian Great Lakes. Environ Sci Technol. 2011 Jan 15;45(2):693-9. doi: 10.1021/es1027844. Epub 2010 Dec 6. PubMed PMID: 21133428. 14: Bandala ER, Andres-Octaviano J, Pastrana P, Torres LG. Removal of aldrin, dieldrin, heptachlor, and heptachlor epoxide using activated carbon and/or Pseudomonas fluorescens free cell cultures. J Environ Sci Health B. 2006;41(5):553-69. PubMed PMID: 16785166. 15: Carr RL, Couch TA, Liu J, Coats JR, Chambers JE. The interaction of chlorinated alicyclic insecticides with brain GABA(A) receptors in channel catfish (Ictalurus punctatus). J Toxicol Environ Health A. 1999 Apr 23;56(8):543-53. PubMed PMID: 10321384. 16: Simpson CD, Wilcock RJ, Smith TJ, Wilkins AL, Langdon AG. Determination of octanol-water partition coefficients for the major components of technical chlordane. Bull Environ Contam Toxicol. 1995 Jul;55(1):149-53. PubMed PMID: 7663085. 17: Elia VJ, Clark CS, Majeti VA, Gartside PS, MacDonald T, Richdale N, Meyer CR, Van Meer GL, Hunninen K. Hazardous chemical exposure at a municipal wastewater treatment plant. Environ Res. 1983 Dec;32(2):360-71. PubMed PMID: 6641669. 18: Lurker PA, Clark CS, Elia VJ, Gartside PS, Kinman RN. Worker exposure to chlorinated organic compounds from the activated-sludge wastewater treatment process. Am Ind Hyg Assoc J. 1983 Feb;44(2):109-12. PubMed PMID: 6837435. 19: Horii S, Miyazaki T, Kaneko S, Akiyama K, Yamagishi T. Identification of gamma-chlordene in freshwater fish from the Tama River (Japan). Bull Environ Contam Toxicol. 1981 Feb;26(2):254-7. PubMed PMID: 7248549. 20: Doherty MJ, Khan MA. Hepatic microsomal mixed-function oxidase in the frog, Xenopus laevis. Comp Biochem Physiol C. 1981;68C(2):221-8. PubMed PMID: 6112107.