KF 14124 | CAS#134186-26-8 | anti-ischemic

MedKoo Cat#: 597369 | Name: KF 14124

Description:

WARNING: This product is for research use only, not for human or veterinary use.

KF 14124 showed potent anti-ischemic activity in a lysine-vasopressin-induced angina pectoris model (rats).

Chemical Structure

KF 14124

CAS#134186-26-8

Theoretical Analysis

MedKoo Cat#: 597369

Name: KF 14124

CAS#: 134186-26-8

Chemical Formula: C19H27N3O5S

Exact Mass: 409.1671

Molecular Weight: 409.50

Elemental Analysis: C, 55.73; H, 6.65; N, 10.26; O, 19.53; S, 7.83

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

KF 14124; KF-14124; KF14124; Dptpp-2-ismn;

IUPAC/Chemical Name

(3S,3aS,6S,6aR)-6-(4-(3-(phenylthio)propyl)piperazin-1-yl)hexahydrofuro[3,2-b]furan-3-yl nitrate

InChi Key

IHHFECHILHHROD-INDMIFKZSA-N

InChi Code

InChI=1S/C19H27N3O5S/c23-22(24)27-17-14-26-18-16(13-25-19(17)18)21-10-8-20(9-11-21)7-4-12-28-15-5-2-1-3-6-15/h1-3,5-6,16-19H,4,7-14H2/t16-,17-,18+,19+/m0/s1

SMILES Code

O=[N+]([O-])O[C@H]1CO[C@H]2[C@@H]1OC[C@@H]2N(CC3)CCN3CCCSc4ccccc4

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 409.50 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Hayashi H, Ikeda J, Kubo K, Moriyama T, Karasawa A, Suzuki F. 1,4:3,6-Dianhydrohexitol nitrate derivatives. II. Synthesis and antianginal activity of aryl- or arylcarbonylpiperazine derivatives. Chem Pharm Bull (Tokyo). 1993 Jun;41(6):1100-10. PubMed PMID: 8370110. 2: Hayashi H, Ikeda J, Kuroda T, Kubo K, Sano T, Suzuki F. 1,4:3,6-Dianhydrohexitol nitrate derivatives. I. Synthesis and antianginal activity of alkylpiperazine derivatives. Chem Pharm Bull (Tokyo). 1993 Jun;41(6):1091-9. PubMed PMID: 8370109.