MedKoo Cat#: 121102 | Name: Ulonivirine
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Ulonivirine is a novel HIV-1 nonnucleoside reverse transcriptase inhibitor in clinical development with potential for once-weekly oral administration for the treatment of HIV-1 infection.

Chemical Structure

Ulonivirine
Ulonivirine
CAS#1591823-76-5

Theoretical Analysis

MedKoo Cat#: 121102

Name: Ulonivirine

CAS#: 1591823-76-5

Chemical Formula: C18H8ClF6N5O3

Exact Mass: 491.0220

Molecular Weight: 491.73

Elemental Analysis: C, 43.97; H, 1.64; Cl, 7.21; F, 23.18; N, 14.24; O, 9.76

Price and Availability

Size Price Availability Quantity
5mg USD 450.00 2 Weeks
25mg USD 950.00 2 Weeks
100mg USD 1,650.00 2 Weeks
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Related CAS #
No Data
Synonym
Ulonivirine; MK-8507; MK8507; MK 8507
IUPAC/Chemical Name
3-chloro-5-{[6-oxo-1-{[6-oxo-5-(trifluoromethyl)-1,6- dihydropyridazin-3-yl]methyl}-4-(trifluoromethyl)-1,6- dihydropyrimidin-5-yl]oxy}benzonitrile
InChi Key
YSFHLBYWQCLYIY-UHFFFAOYSA-N
InChi Code
InChI=1S/C18H8ClF6N5O3/c19-9-1-8(5-26)2-11(3-9)33-13-14(18(23,24)25)27-7-30(16(13)32)6-10-4-12(17(20,21)22)15(31)29-28-10/h1-4,7H,6H2,(H,29,31)
SMILES Code
O=C1C(C(F)(F)F)=CC(CN(C=NC(C(F)(F)F)=C2OC3=CC(C#N)=CC(Cl)=C3)C2=O)=NN1
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 491.73 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Ankrom W, Jackson Rudd D, Schaeffer A, Panebianco D, Friedman EJ, Tomek C, Stoch SA, Iwamoto M. Pharmacokinetic and Safety Profile of the Novel HIV Nonnucleoside Reverse Transcriptase Inhibitor MK-8507 in Adults without HIV. Antimicrob Agents Chemother. 2021 Nov 17;65(12):e0093521. doi: 10.1128/AAC.00935-21. Epub 2021 Sep 13. PMID: 34516246; PMCID: PMC8597757.