Triglutamate folate | CAS#29701-38-0 | bioactive chemical

MedKoo Cat#: 597242 | Name: Triglutamate folate

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Triglutamate folate is a bioactive chemical.

Chemical Structure

Triglutamate folate

CAS#29701-38-0

Theoretical Analysis

MedKoo Cat#: 597242

Name: Triglutamate folate

CAS#: 29701-38-0

Chemical Formula: C34H40N10O15

Exact Mass: 828.2675

Molecular Weight: 828.74

Elemental Analysis: C, 49.28; H, 4.87; N, 16.90; O, 28.96

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Triglutamate folate; Pteglu3;

IUPAC/Chemical Name

(3S,8S,13S,18S)-1-(4-(((2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl)amino)phenyl)-1,6,11,16-tetraoxo-2,7,12,17-tetraazaicosane-3,8,13,18,20-pentacarboxylic acid

InChi Key

YMUKRFYNHZWDBN-TUFLPTIASA-N

InChi Code

InChI=1S/C34H40N10O15/c35-34-43-27-26(29(51)44-34)38-17(14-37-27)13-36-16-3-1-15(2-4-16)28(50)42-21(33(58)59)7-11-24(47)40-19(31(54)55)5-9-22(45)39-18(30(52)53)6-10-23(46)41-20(32(56)57)8-12-25(48)49/h1-4,14,18-21,36H,5-13H2,(H,39,45)(H,40,47)(H,41,46)(H,42,50)(H,48,49)(H,52,53)(H,54,55)(H,56,57)(H,58,59)(H3,35,37,43,44,51)/t18-,19-,20-,21-/m0/s1

SMILES Code

O=C(O)CC[C@@H](C(O)=O)NC(CC[C@@H](C(O)=O)NC(CC[C@@H](C(O)=O)NC(CC[C@@H](C(O)=O)NC(C1=CC=C(NCC2=CN=C3NC(N)=NC(C3=N2)=O)C=C1)=O)=O)=O)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 828.74 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Gregory JF 3rd, Ink SL, Cerda JJ. Comparison of pteroylpolyglutamate hydrolase (folate conjugase) from porcine and human intestinal brush border membrane. Comp Biochem Physiol B. 1987;88(4):1135-41. PubMed PMID: 3427931. 2: Lockshin A, Mondal K, Danenberg PV. Spectroscopic studies of ternary complexes of thymidylate synthetase, deoxyribonucleotides, and folate analogs. J Biol Chem. 1984 Sep 25;259(18):11346-52. PubMed PMID: 6236224. 3: Pratt RF, Cooper BA. Folates in plasma and bile of man after feeding folic acid--3H and 5-formyltetrahydrofolate (folinic acid). J Clin Invest. 1971 Feb;50(2):455-62. PubMed PMID: 4992993; PubMed Central PMCID: PMC291942.