Dioleoylmethotrexate | CAS#141456-07-7 | antineoplastic

MedKoo Cat#: 597199 | Name: Dioleoylmethotrexate

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Dioleoylmethotrexate is an antineoplastic drug.

Chemical Structure

Dioleoylmethotrexate

CAS#141456-07-7

Theoretical Analysis

MedKoo Cat#: 597199

Name: Dioleoylmethotrexate

CAS#: 141456-07-7

Chemical Formula: C56H86N8O7

Exact Mass: 982.6619

Molecular Weight: 983.35

Elemental Analysis: C, 68.40; H, 8.82; N, 11.40; O, 11.39

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Dioleoylmethotrexate;

IUPAC/Chemical Name

L-Glutamic acid, N-(4-(((2,4-diamino-6-pteridinyl)methyl)methylamino)benzoyl)-, dianhydride with 9-octadecenoic acid, (Z,Z)-

InChi Key

CEXMEEOLEIGTPF-NJENFTAUSA-N

InChi Code

InChI=1S/C56H86N8O7/c1-4-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-48(65)70-50(67)41-40-47(55(69)71-49(66)35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-5-2)61-54(68)44-36-38-46(39-37-44)64(3)43-45-42-59-53-51(60-45)52(57)62-56(58)63-53/h18-21,36-39,42,47H,4-17,22-35,40-41,43H2,1-3H3,(H,61,68)(H4,57,58,59,62,63)/b20-18+,21-19+/t47-/m1/s1

SMILES Code

CCCCCCCC/C=C/CCCCCCCC(OC(CC[C@H](C(OC(CCCCCCC/C=C/CCCCCCCC)=O)=O)NC(c1ccc(N(Cc2nc3c(N)nc(N)nc3nc2)C)cc1)=O)=O)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 983.35 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: de Smidt PC, van Berkel TJ. Prolonged serum half-life of antineoplastic drugs by incorporation into the low density lipoprotein. Cancer Res. 1990 Dec 1;50(23):7476-82. PubMed PMID: 2147578.