MedKoo Cat#: 591718 | Name: Sulfiram
Featured

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Sulfiram or monosulfiram, trade name Tetmosol, is an ectoparasiticide used in the treatment and prevention of scabies. It is usually sold as a solution or medicated soap, sometimes in combination with benzyl benzoate.

Chemical Structure

Sulfiram
Sulfiram
CAS#95-05-6

Theoretical Analysis

MedKoo Cat#: 591718

Name: Sulfiram

CAS#: 95-05-6

Chemical Formula: C10H20N2S3

Exact Mass: 264.0789

Molecular Weight: 264.46

Elemental Analysis: C, 45.42; H, 7.62; N, 10.59; S, 36.37

Price and Availability

Size Price Availability Quantity
250mg USD 650.00
Bulk Inquiry
Buy Now
Add to Cart
Related CAS #
No Data
Synonym
Sulfiram; NSC 36731; NSC-36731; NSC36731
IUPAC/Chemical Name
Sulfide, bis(diethylthiocarbamoyl)
InChi Key
CTPKSRZFJSJGML-UHFFFAOYSA-N
InChi Code
InChI=1S/C10H20N2S3/c1-5-11(6-2)9(13)15-10(14)12(7-3)8-4/h5-8H2,1-4H3
SMILES Code
S=C(SC(N(CC)CC)=S)N(CC)CC
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 264.46 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Berthe-Aucejo A, Prot-Labarthe S, Pull L, Lorrot M, Touratier S, Trout H, Bourdon O, Dehen L, Bourrat E. Traitement de la gale et rupture d'Ascabiol(®) : quid de la population pédiatrique ? Gale chez l'enfant et rupture d'Ascabiol(®) [Treatment of scabies and Ascabiol(®) supply disruption: what about the pediatric population?]. Arch Pediatr. 2014 Jun;21(6):670-5. French. doi: 10.1016/j.arcped.2014.03.001. Epub 2014 Apr 24. PMID: 24768069. 2: Libeu CA, Descamps O, Zhang Q, John V, Bredesen DE. Altering APP proteolysis: increasing sAPPalpha production by targeting dimerization of the APP ectodomain. PLoS One. 2012;7(6):e40027. doi: 10.1371/journal.pone.0040027. Epub 2012 Jun 29. PMID: 22768208; PMCID: PMC3386930. 3: Buffet M, Dupin N. Current treatments for scabies. Fundam Clin Pharmacol. 2003 Apr;17(2):217-25. doi: 10.1046/j.1472-8206.2003.00173.x. PMID: 12667233. 4: Diagnosis and treatment of scabies in 2002: rapid diagnosis and proper management limit the risk of spread. Prescrire Int. 2002 Oct;11(61):152-5. PMID: 12378748. 5: Pitche P, Wolkenstein P, Cremer G, Foulet F, Lascaux AS, Revuz J. Gale profuse: cinétique de guérison parasitologique avec l'association benzoate de benzyl et sulfiram [Profuse scabies: kinetic curves of parasitologic cure with an association of benzyl benzoate and sulfiram]. Ann Dermatol Venereol. 2002 Mar;129(3):287-9. French. PMID: 11988682. 6: Reid JM, Kuffel MJ, Miller JK, Rios R, Ames MM. Metabolic activation of dacarbazine by human cytochromes P450: the role of CYP1A1, CYP1A2, and CYP2E1. Clin Cancer Res. 1999 Aug;5(8):2192-7. PMID: 10473105. 7: Mays DC, Nelson AN, Benson LM, Johnson KL, Naylor S, Lipsky JJ. Photolysis of sulfiram: a mechanism for its disulfiram-like reaction. Biochem Pharmacol. 1994 Nov 16;48(10):1917-25. doi: 10.1016/0006-2952(94)90590-8. PMID: 7986203.