MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 558203 | Name: Cymbush R

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Cymbush R is a bioactive chemical.

Chemical Structure

Cymbush R
Cymbush R
CAS#66841-24-5

Theoretical Analysis

MedKoo Cat#: 558203

Name: Cymbush R

CAS#: 66841-24-5

Chemical Formula: C22H19Cl2NO3

Exact Mass: 415.0700

Molecular Weight: 416.30

Elemental Analysis: C, 63.47; H, 4.60; Cl, 17.03; N, 3.36; O, 11.53

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
Cymbush R; Caswell No. 271DD; Cymbush R;
IUPAC/Chemical Name
alpha-Cyano-3-phenoxybenzyl (1R-(1alpha(R*),3beta))-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate
InChi Key
KAATUXNTWXVJKI-CMKODMSKSA-N
InChi Code
InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17-,18-,20+/m0/s1
SMILES Code
O=C([C@@H]1C(C)(C)[C@H]1/C=C(Cl)\Cl)O[C@@H](C#N)C2=CC=CC(OC3=CC=CC=C3)=C2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 416.30 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Muyobela J, Nkunika PO, Mwase ET. Resistance status of ticks (Acari; Ixodidae) to amitraz and cypermethrin acaricides in Isoka District, Zambia. Trop Anim Health Prod. 2015 Dec;47(8):1599-605. doi: 10.1007/s11250-015-0906-4. Epub 2015 Aug 27. PubMed PMID: 26310511. 2: Nandi A, Jyoti, Singh H, Singh NK. Esterase and glutathione S-transferase levels associated with synthetic pyrethroid resistance in Hyalomma anatolicum and Rhipicephalus microplus ticks from Punjab, India. Exp Appl Acarol. 2015 May;66(1):141-57. doi: 10.1007/s10493-015-9884-5. Epub 2015 Feb 5. PubMed PMID: 25652614. 3: Yan J, Zhang P, Wang X, Xu M, Wang Y, Zhou Z, Zhu W. Stereoselective Degradation of alpha-Cypermethrin and Its Enantiomers in Rat Liver Microsomes. Chirality. 2016 Jan;28(1):58-64. doi: 10.1002/chir.22538. Epub 2015 Oct 8. PubMed PMID: 26448061. 4: Rodriguez-Vivas RI, Hodgkinson JE, Rosado-Aguilar JA, Villegas-Perez SL, Trees AJ. The prevalence of pyrethroid resistance phenotype and genotype in Rhipicephalus (Boophilus) microplus in Yucatan, Mexico. Vet Parasitol. 2012 Mar 23;184(2-4):221-9. doi: 10.1016/j.vetpar.2011.09.017. Epub 2011 Sep 16. PubMed PMID: 21978740. 5: Zhao J, Chi Y, Liu F, Jia D, Yao K. Effects of Two Surfactants and Beta-Cyclodextrin on Beta-Cypermethrin Degradation by Bacillus licheniformis B-1. J Agric Food Chem. 2015 Dec 23;63(50):10729-35. doi: 10.1021/acs.jafc.5b04485. Epub 2015 Dec 8. PubMed PMID: 26615963. 6: Kasimoglu C, Uysal H. Mutagenic biomonitoring of pirethroid insecticides in human lymphocyte cultures: use of micronuclei as biomarkers and recovery by Rosa canina extracts of mutagenic effects. Pharm Biol. 2015 May;53(5):625-9. doi: 10.3109/13880209.2014.935865. Epub 2014 Oct 21. PubMed PMID: 25330814. 7: Godara R, Katoch R, Yadav A, Ahanger RR, Bhutyal AD, Verma PK, Katoch M, Dutta S, Nisa F, Singh NK. In vitro acaricidal activity of ethanolic and aqueous floral extracts of Calendula officinalis against synthetic pyrethroid resistant Rhipicephalus (Boophilus) microplus. Exp Appl Acarol. 2015 Sep;67(1):147-57. doi: 10.1007/s10493-015-9929-9. Epub 2015 Jun 14. PubMed PMID: 26071101. 8: Banek K, Kilian A, Allan R. Evaluation of Interceptor long-lasting insecticidal nets in eight communities in Liberia. Malar J. 2010 Mar 24;9:84. doi: 10.1186/1475-2875-9-84. PubMed PMID: 20334677; PubMed Central PMCID: PMC2858215. 9: Quan LF, Qiu GS, Zhang HJ, Sun LN, Li YY, Yan WT. Sublethal Concentration of Beta-Cypermethrin Influences Fecundity and Mating Behavior of Carposina sasakii (Lepidoptera: Carposinidae) Adults. J Econ Entomol. 2016 Oct;109(5):2196-204. doi: 10.1093/jee/tow170. Epub 2016 Aug 6. PubMed PMID: 27498114. 10: Abedi Z, Saber M, Gharekhani G, Mehrvar A, Kamita SG. Lethal and sublethal effects of azadirachtin and cypermethrin on Habrobracon hebetor (Hymenoptera: Braconidae). J Econ Entomol. 2014 Apr;107(2):638-45. PubMed PMID: 24772544. 11: Singh NK, Jyoti, Haque M, Singh H, Rath SS, Ghosh S. A comparative study on cypermethrin resistance in Rhipicephalus (Boophilus) microplus and Hyalomma anatolicum from Punjab (India). Ticks Tick Borne Dis. 2014 Mar;5(2):90-4. doi: 10.1016/j.ttbdis.2013.08.002. Epub 2013 Nov 16. PubMed PMID: 24252261. 12: Fernández-Salas A, Rodríguez-Vivas RI, Alonso-Díaz MÁ. Resistance of Rhipicephalus microplus to amitraz and cypermethrin in tropical cattle farms in Veracruz, Mexico. J Parasitol. 2012 Oct;98(5):1010-4. doi: 10.1645/GE-3074.1. Epub 2012 Apr 23. PubMed PMID: 22524292. 13: Corrêa RR, Lopes WD, Teixeira WF, Cruz BC, Gomes LV, Felippelli G, Maciel WG, Fávero FC, Buzzulini C, Bichuette MA, Soares VE, da Costa AJ. A comparison of three different methodologies for evaluating Rhipicephalus (Boophilus) microplus susceptibility to topical spray compounds. Vet Parasitol. 2015 Jan 15;207(1-2):115-24. doi: 10.1016/j.vetpar.2014.11.001. Epub 2014 Nov 15. PubMed PMID: 25468670. 14: Pessoa GC, Rosa AC, Cavalari L, Rezende JG, de Mello BV, Diotaiuti L. Susceptibility of Triatoma sordida Stal, 1859 (Hemiptera: Reduviidae) to alpha-cypermethrin under natural climatic conditions. Rev Soc Bras Med Trop. 2015 Jul-Aug;48(4):422-6. doi: 10.1590/0037-8682-0097-2015. PubMed PMID: 26312932. 15: Cruz BC, Buzzulini C, Lopes WD, Maciel WG, Bichuette MA, Felippelli G, Teixeira WF, Soares VE, Gomes LV, Prando L, Campos GP, da Costa AJ. Effects of different spray formulations on the reproductive parameters of engorged Rhipicephalus (Boophilus) microplus females detached from experimentally infested cattle. Prev Vet Med. 2015 Nov 1;122(1-2):70-5. doi: 10.1016/j.prevetmed.2015.09.010. Epub 2015 Sep 25. PubMed PMID: 26427633. 16: Kavvalakis MP, Tzatzarakis MN, Alegakis AK, Vynias D, Tsakalof AK, Tsatsakis AM. Development and application of GC-MS method for monitoring of long-term exposure to the pesticide cypermethrin. Drug Test Anal. 2014 Jun;6 Suppl 1:9-16. doi: 10.1002/dta.1601. PubMed PMID: 24817043. 17: Zuo Y, Peng X, Wang K, Lin F, Li Y, Chen M. Expression patterns, mutation detection and RNA interference of Rhopalosiphum padi voltage-gated sodium channel genes. Sci Rep. 2016 Jul 21;6:30166. doi: 10.1038/srep30166. PubMed PMID: 27439594; PubMed Central PMCID: PMC4954994. 18: Zhang S, Zhang X, Shen J, Mao K, You H, Li J. Susceptibility of field populations of the diamondback moth, Plutella xylostella, to a selection of insecticides in Central China. Pestic Biochem Physiol. 2016 Sep;132:38-46. doi: 10.1016/j.pestbp.2016.01.007. Epub 2016 Jan 27. PubMed PMID: 27521911. 19: Taju G, Abdul Majeed S, Nambi KS, Farook MA, Vimal S, Sahul Hameed AS. In vitro cytotoxic, genotoxic and oxidative stress of cypermethrin on five fish cell lines. Pestic Biochem Physiol. 2014 Jul;113:15-24. doi: 10.1016/j.pestbp.2014.06.006. Epub 2014 Jun 24. PubMed PMID: 25052522. 20: Torres JB, Rodrigues AR, Barros EM, Santos DS. Lambda-Cyhalothrin Resistance in the Lady Beetle Eriopis connexa (Coleoptera: Coccinellidae) Confers Tolerance to Other Pyrethroids. J Econ Entomol. 2015 Feb;108(1):60-8. doi: 10.1093/jee/tou035. Epub 2015 Jan 24. PubMed PMID: 26470104.

View History

Furanodiene

Furanodiene

VU937

VU937

Cytostatin

Cytostatin