Synonym
Cysteine hydrazide; Cysteine, hydrazide, L-; L-Cysteine, hydrazide;
IUPAC/Chemical Name
(R)-2-amino-3-mercaptopropanehydrazide
InChi Key
IQIYDJRAZKPGKO-REOHCLBHSA-N
InChi Code
InChI=1S/C3H9N3OS/c4-2(1-8)3(7)6-5/h2,8H,1,4-5H2,(H,6,7)/t2-/m0/s1
SMILES Code
N[C@@H](CS)C(NN)=O
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
135.18
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
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5: Błaszczyk B, Giełdanowski J, Woźniak M, Dobryszycka W, Lemmel EM, Katkiewicz M, Viljanen M. Azimexone and cysteine hydrazide in the treatment of allergic encephalomyelitis. Arch Immunol Ther Exp (Warsz). 1988;36(3):217-27. PubMed PMID: 3266915.
6: Wieczorek Z, Spiegel K, Ryzewski J, Zimecki M. Effect of hydrazide cysteine on the humoral immune response of mice to sheep erythrocytes. Arch Immunol Ther Exp (Warsz). 1987;35(2):193-200. PubMed PMID: 3447534.
7: Zimecki M, Zwoliński J, Ryzewski J, Wieczorek Z. Effect of hydrazide cysteine on T cells. II. Human autologous rosette forming cells belong to two subpopulations differing with respect to the sensitivity to hydrocortisone and hydrazide cysteine. Arch Immunol Ther Exp (Warsz). 1984;32(3):281-5. PubMed PMID: 6335390.
8: Zimecki M, Ryzewski J, Wieczorek Z. Effect of hydrazide cysteine on T cells. I. Hydrazide cysteine changes the sensitivity of murine T lymphocytes to hydrocortisone and their ability to form autologous rosettes. Arch Immunol Ther Exp (Warsz). 1984;32(3):269-79. PubMed PMID: 6335389.
9: Ryzewski J, Giełdanowski J, Raberger G, Kossakowska M. L-cysteine hydrazide--its pharmacological and immunosuppressive activity. Arch Immunol Ther Exp (Warsz). 1979;27(6):733-47. PubMed PMID: 317699.
10: Kwapiszewski W, Iliaszenko J, Sokołowska-Muszyńska M. Synthesis of L-cysteine derivatives of immunotropic activity. Arch Immunol Ther Exp (Warsz). 1978;26(1-6):917-9. PubMed PMID: 749840.
11: Ryzewski J, Kossakowska M, Krzystyniak K. Influence of the cysteine derivatives on the cell-mediated immunity. Arch Immunol Ther Exp (Warsz). 1978;26(1-6):913-6. PubMed PMID: 749839.
12: Krzystyniak K, Ryzewski J, Chwaliński S. Studies on the influence of thiols on lymphocytes (T-type lymphocytes) functions. Arch Immunol Ther Exp (Warsz). 1978;26(1-6):367-70. PubMed PMID: 312073.
13: Ryzewski J, Krzystyniak K. Studies on the influence of thiols on lymphocytes (T-type lymphocytes) function. Arch Immunol Ther Exp (Warsz). 1978;26(1-6):361-5. PubMed PMID: 312072.
