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MedKoo Cat#: 591511 | Name: AHR-14310C

Description:

WARNING: This product is for research use only, not for human or veterinary use.

AHR-14310C is a potent, long-acting, nonsedating H1-antihistamine that prevents antigen-induced mucus formation.

Chemical Structure

AHR-14310C
AHR-14310C
CAS#119810-68-3

Theoretical Analysis

MedKoo Cat#: 591511

Name: AHR-14310C

CAS#: 119810-68-3

Chemical Formula: C24H28F2N2O3

Exact Mass: 430.2068

Molecular Weight: 430.50

Elemental Analysis: C, 66.96; H, 6.56; F, 8.83; N, 6.51; O, 11.15

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
AHR-14310C; AHR14310C; AHR 14310C
IUPAC/Chemical Name
2-Oxazolidinone, 5-(2-(4-(bis(4-fluorophenyl)hydroxymethyl-1-piperidinyl)ethyl)-3-methyl)-
InChi Key
SFIREZNAZLSKNE-QFIPXVFZSA-N
InChi Code
InChI=1S/C24H28F2N2O3/c1-27-16-22(31-23(27)29)12-15-28-13-10-19(11-14-28)24(30,17-2-6-20(25)7-3-17)18-4-8-21(26)9-5-18/h2-9,19,22,30H,10-16H2,1H3/t22-/m0/s1
SMILES Code
OC(c1ccc(F)cc1)(c2ccc(F)cc2)C(CC3)CCN3CC[C@H]4CN(C)C(O4)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 430.50 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Nolan JC, Foxwell MH, Whitman LL, Yanni JM, Walsh DA, Kilpatrick BF, Johnson DN, Proakis AG. AHR-14310C: a potent, long-acting, nonsedating H1-antihistamine that prevents antigen-induced mucus formation in sensitive rats. J Pharmacol Exp Ther. 1990 Jun;253(3):1177-83. PubMed PMID: 1972750.