UK 88947 | CAS#137015-76-0 | protease inhibitor

MedKoo Cat#: 596903 | Name: UK-88947 HCl

Description:

WARNING: This product is for research use only, not for human or veterinary use.

UK 88947 is a protease inhibitor.

Chemical Structure

UK-88947 HCl

CAS#137015-76-0 (HCl)

Theoretical Analysis

MedKoo Cat#: 596903

Name: UK-88947 HCl

CAS#: 137015-76-0 (HCl)

Chemical Formula: C40H60ClN5O7

Exact Mass:

Molecular Weight: 758.39

Elemental Analysis: C, 63.35; H, 7.97; Cl, 4.67; N, 9.23; O, 14.77

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

137015-76-0 (HCl)

Synonym

UK 88947; UK-88947; UK88947; UK-88,947; UK 88,947; UK88,947;

IUPAC/Chemical Name

(3S)-3-((S)-2-(1-aminocyclohexane-1-carboxamido)-3-phenylpropanamido)-4-(((2S,5R)-3-hydroxy-5-(isobutylcarbamoyl)-7-methyl-1-phenyloctan-2-yl)amino)-4-oxobutanoic acid hydrochloride

InChi Key

OSKPXYCTBWIRIE-YVITZFCESA-N

InChi Code

InChI=1S/C40H59N5O7.ClH/c1-26(2)20-30(36(49)42-25-27(3)4)23-34(46)31(21-28-14-8-5-9-15-28)43-38(51)33(24-35(47)48)44-37(50)32(22-29-16-10-6-11-17-29)45-39(52)40(41)18-12-7-13-19-40;/h5-6,8-11,14-17,26-27,30-34,46H,7,12-13,18-25,41H2,1-4H3,(H,42,49)(H,43,51)(H,44,50)(H,45,52)(H,47,48);1H/t30-,31+,32+,33+,34?;/m1./s1

SMILES Code

O=C(O)C[C@@H](C(N[C@@H](CC1=CC=CC=C1)C(O)C[C@H](C(NCC(C)C)=O)CC(C)C)=O)NC([C@H](CC2=CC=CC=C2)NC(C3(N)CCCCC3)=O)=O.[H]Cl

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 758.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Nagy K, Young M, Baboonian C, Merson J, Whittle P, Oroszlan S. Antiviral activity of human immunodeficiency virus type 1 protease inhibitors in a single cycle of infection: evidence for a role of protease in the early phase. J Virol. 1994 Feb;68(2):757-65. PubMed PMID: 8289379; PubMed Central PMCID: PMC236512. 2: Baboonian C, Dalgleish A, Bountiff L, Gross J, Oroszlan S, Rickett G, Smith-Burchnell C, Troke P, Merson J. HIV-1 proteinase is required for synthesis of pro-viral DNA. Biochem Biophys Res Commun. 1991 Aug 30;179(1):17-24. Erratum in: Biochem Biophys Res Commun 1992 Sep 16;187(2):1200. PubMed PMID: 1652947.