MedKoo Cat#: 596840 | Name: Oglufanide TFA

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Oglufanide is a synthetic dipeptide immunomodulator in development for the treatment of chronic hepatitis C viral infection. Oglufanide was originally developed to treat severe infectious disease. Oglufanide works as a regulator of the body's immune response, is being given by intranasal administration to patients with chronic hepatitis C viral infection. It has a role as a metabolite, an immunomodulator, an angiogenesis modulating agent and an antineoplastic agent. It is functionally related to a L-glutamic acid and a L-tryptophan.

Chemical Structure

Oglufanide TFA
Oglufanide TFA
CAS#2517564-81-5 (TFA)

Theoretical Analysis

MedKoo Cat#: 596840

Name: Oglufanide TFA

CAS#: 2517564-81-5 (TFA)

Chemical Formula: C16H17N3Na2O5

Exact Mass: 0.0000

Molecular Weight: 377.30

Elemental Analysis: C, 50.93; H, 4.54; N, 11.14; Na, 12.19; O, 21.20

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Synonym
L-Glutamyl-L-tryptophan; Glutamyltryptophan; IM 862; NSC 334073; Oglufanide; Thymogen; Timogen; α-Glu-Trp;
IUPAC/Chemical Name
sodium (S)-4-amino-5-(((S)-1-carboxylato-2-(1H-indol-3-yl)ethyl)amino)-5-oxopentanoate
InChi Key
GDLPAGOVHZLZEK-JBUFHSOLSA-L
InChi Code
InChI=1S/C16H19N3O5.2Na/c17-11(5-6-14(20)21)15(22)19-13(16(23)24)7-9-8-18-12-4-2-1-3-10(9)12;;/h1-4,8,11,13,18H,5-7,17H2,(H,19,22)(H,20,21)(H,23,24);;/q;2*+1/p-2/t11-,13-;;/m0../s1
SMILES Code
O=C([O-])[C@H](CC1=CNC2=C1C=CC=C2)NC([C@H](CCC([O-])=O)N)=O.[Na+].[Na+]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 377.30 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Cattelan AM, Trevenzoli M, Aversa SM. Recent advances in the treatment of AIDS-related Kaposi's sarcoma. Am J Clin Dermatol. 2002;3(7):451-62. Review. PubMed PMID: 12180893.