L 681217 | CAS#93522-10-2 | glycolipid-type antibiotic

MedKoo Cat#: 596630 | Name: L 681217

Description:

WARNING: This product is for research use only, not for human or veterinary use.

L 681217 is a glycolipid-type antibiotic related to the efrotomycin class, isolated from a Streptomyces sp.. L 681,217 shows broad spectrum antibiotic activity against Gram positive and Gram negative bacteria. L-681,217 inhibits bacterial protein synthesis at the elongation stage, its target being elongation factor Tu.

Chemical Structure

L 681217

CAS#93522-10-2

Theoretical Analysis

MedKoo Cat#: 596630

Name: L 681217

CAS#: 93522-10-2

Chemical Formula: C36H53NO10

Exact Mass: 659.3669

Molecular Weight: 659.81

Elemental Analysis: C, 65.53; H, 8.10; N, 2.12; O, 24.25

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

L 681217; L-681217; L681217; L-681,217; L681,217; L 681,217;

IUPAC/Chemical Name

(2E,4E,6E)-7-(3-hydroxy-5-((4E,6E)-3-methoxy-4-methyl-8-(2-(2,4,5-trihydroxy-5-methyl-6-((1E,3E)-penta-1,3-dien-1-yl)tetrahydro-2H-pyran-2-yl)butanamido)octa-4,6-dien-2-yl)tetrahydrofuran-2-yl)hepta-2,4,6-trienoic acid

InChi Key

OSKAZZUZQORABG-UQKUNJBPSA-N

InChi Code

InChI=1S/C36H53NO10/c1-7-9-12-19-31-35(5,43)30(39)23-36(44,47-31)26(8-2)34(42)37-21-16-15-17-24(3)33(45-6)25(4)29-22-27(38)28(46-29)18-13-10-11-14-20-32(40)41/h7,9-20,25-31,33,38-39,43-44H,8,21-23H2,1-6H3,(H,37,42)(H,40,41)/b9-7+,11-10+,16-15+,18-13+,19-12+,20-14+,24-17+

SMILES Code

O=C(O)/C=C/C=C/C=C/C1OC(C(C)C(OC)/C(C)=C/C=C/CNC(C(C2(O)CC(O)C(C)(O)C(/C=C/C=C/C)O2)CC)=O)CC1O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 659.81 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Kempf AJ, Wilson KE, Hensens OD, Monaghan RL, Zimmerman SB, Dulaney EL. L-681,217, a new and novel member of the efrotomycin family of antibiotics. J Antibiot (Tokyo). 1986 Oct;39(10):1361-7. PubMed PMID: 3781906.