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MedKoo Cat#: 596542 | Name: Hydroxyproline
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Hydroxyproline is a hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.

Chemical Structure

Hydroxyproline
Hydroxyproline
CAS#51-35-4

Theoretical Analysis

MedKoo Cat#: 596542

Name: Hydroxyproline

CAS#: 51-35-4

Chemical Formula: C5H9NO3

Exact Mass: 131.0582

Molecular Weight: 131.13

Elemental Analysis: C, 45.80; H, 6.92; N, 10.68; O, 36.60

Price and Availability

Size Price Availability Quantity
5g USD 250.00 2 Weeks
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Related CAS #
No Data
Synonym
Hydroxyproline; Oxaceprol; NSC 46704; NSC-46704; NSC46704;
IUPAC/Chemical Name
(2S)-4-hydroxypyrrolidine-2-carboxylic acid
InChi Key
PMMYEEVYMWASQN-BKLSDQPFSA-N
InChi Code
InChI=1S/C5H9NO3/c7-3-1-4(5(8)9)6-2-3/h3-4,6-7H,1-2H2,(H,8,9)/t3?,4-/m0/s1
SMILES Code
OC1C[C@@H](C(O)=O)NC1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 131.13 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
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PubMed PMID: 29789577; PubMed Central PMCID: PMC5964236. 8: Geng J, Zhao Z, Yang L, Zhang M, Liu X. Protein Kinase D was involved in vascular remodeling in spontaneously hypertensive rats. Clin Exp Hypertens. 2018 May 21:1-8. doi: 10.1080/10641963.2018.1469647. [Epub ahead of print] PubMed PMID: 29781735. 9: Ugwu DI, Okoro UC, Mishra NK. Synthesis of proline derived benzenesulfonamides: A potent anti-Trypanosoma brucei gambiense agent. Eur J Med Chem. 2018 May 14;154:110-116. doi: 10.1016/j.ejmech.2018.05.017. [Epub ahead of print] PubMed PMID: 29778893. 10: Tagkalos E, Heimann A, Gaiser T, Hirsch D, Gockel I, Lang H, Jansen-Winkeln B. Cecal Resection with Bipolar Sealing Devices in a Rat Model. J Invest Surg. 2018 May 18:1-8. doi: 10.1080/08941939.2018.1469698. [Epub ahead of print] PubMed PMID: 29775392. 11: George Kallivalappil G, Kuttan G. Efficacy of punarnavine in restraining organ-specific tumour progression in 4T1-induced murine breast tumour model. Inflammopharmacology. 2018 May 17. doi: 10.1007/s10787-018-0490-0. [Epub ahead of print] PubMed PMID: 29770894. 12: Wen J, Jiang W, Feng L, Kuang S, Jiang J, Tang L, Zhou X, Liu Y. The influence of graded levels of available phosphorus on growth performance, muscle antioxidant and flesh quality of young grass carp (Ctenopharyngodon idella). Anim Nutr. 2015 Jun;1(2):77-84. doi: 10.1016/j.aninu.2015.05.004. Epub 2015 May 22. PubMed PMID: 29767010; PubMed Central PMCID: PMC5884464. 13: Daglioglu YK, Duzgun O, Sarici IS, Ulutas KT. Comparison of platelet rich plasma versus fibrin glue on colonic anastomoses in rats. Acta Cir Bras. 2018 Apr;33(4):333-340. doi: 10.1590/s0102-865020180040000005. PubMed PMID: 29768536. 14: Yi F, Wang L, Wang M, Yuan XL, Wan HJ, Li JY. [Combined effect of gestational age and birth weight on metabolites related to inherited metabolic diseases in neonates]. Zhongguo Dang Dai Er Ke Za Zhi. 2018 May;20(5):352-357. Chinese. PubMed PMID: 29764569. 15: Fayed MR, El-Naga RN, Akool ES, El-Demerdash E. The potential antifibrotic impact of apocynin and alpha-lipoic acid in concanavalin A-induced liver fibrosis in rats: Role of NADPH oxidases 1 and 4. Drug Discov Ther. 2018;12(2):58-67. doi: 10.5582/ddt.2017.01065. PubMed PMID: 29760339. 16: Guerin S, Syed TAM, Thompson D. Deconstructing collagen piezoelectricity using alanine-hydroxyproline-glycine building blocks. Nanoscale. 2018 May 24;10(20):9653-9663. doi: 10.1039/c8nr01634h. PubMed PMID: 29757342. 17: Shimura H, Mitsui T, Kira S, Ihara T, Sawada N, Nakagomi H, Miyamoto T, Tsuchiya S, Kanda M, Takeda M. Metabolomic Analysis of Overactive Bladder in Male Patients: Identification of Potential Metabolite Biomarkers. Urology. 2018 May 9. pii: S0090-4295(18)30452-7. doi: 10.1016/j.urology.2018.05.001. [Epub ahead of print] PubMed PMID: 29752971. 18: Vidhya S, Ramya R, Coral K, Sulochana KN, Bharathidevi SR. Effect of free amino acids on bovine retinal pericytes. Exp Eye Res. 2018 May 9. pii: S0014-4835(16)30350-5. doi: 10.1016/j.exer.2018.05.004. [Epub ahead of print] PubMed PMID: 29752946. 19: A V T, Dinda AK, Koul V. Evaluation of nano hydrogel composite based on gelatin/HA/CS suffused with Asiatic acid/ZnO and CuO nanoparticles for second degree burns. Mater Sci Eng C Mater Biol Appl. 2018 Aug 1;89:378-386. doi: 10.1016/j.msec.2018.03.034. Epub 2018 Apr 9. PubMed PMID: 29752110. 20: Samareh Fekri M, Mandegary A, Sharififar F, Poursalehi HR, Nematollahi MH, Izadi A, Mehdipour M, Asadi A, Samareh Fekri M. Protective effect of standardized extract of Myrtus communis L. (myrtle) on experimentally bleomycin-induced pulmonary fibrosis: biochemical and histopathological study. Drug Chem Toxicol. 2018 May 11:1-7. doi: 10.1080/01480545.2018.1459670. [Epub ahead of print] PubMed PMID: 29747538.

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