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MedKoo Cat#: 591300 | Name: Afalanine
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Afalanine is a biochemical.

Chemical Structure

Afalanine
CAS#2901-75-9

Theoretical Analysis

MedKoo Cat#: 591300

Name: Afalanine

CAS#: 2901-75-9

Chemical Formula: C11H13NO3

Exact Mass: 207.0895

Molecular Weight: 207.23

Elemental Analysis: C, 63.76; H, 6.32; N, 6.76; O, 23.16

Price and Availability

Size Price Availability Quantity
5g USD 250.00 2 Weeks
25g USD 450.00 2 Weeks
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Related CAS #
No Data
Synonym
Afalanine; NSC 43242; NSC-43242; NSC43242; Ac-DL-Phe-OH; acetylphenylalanine; N-Acetylphenylalanine; N-Acetyl-DL-phenylalanine
IUPAC/Chemical Name
2-acetamido-3-phenylpropanoic acid
InChi Key
CBQJSKKFNMDLON-UHFFFAOYSA-N
InChi Code
InChI=1S/C11H13NO3/c1-8(13)12-10(11(14)15)7-9-5-3-2-4-6-9/h2-6,10H,7H2,1H3,(H,12,13)(H,14,15)
SMILES Code
O=C(O)C(NC(C)=O)CC1=CC=CC=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 207.23 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
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[Epub ahead of print] PubMed PMID: 29847112. 4: Kotsis T, Nastos C, Stamatis K, Chondroudaki I, Pafiti A, Frangou M, Kotsovolou V, Chondros K, Smirniotis V, Fotopoulos A. Insulin Metabolism and Assessment of Hepatic Insulin Extraction During Liver Regeneration. A Study in a Rat Model. J Invest Surg. 2018 May 30:1-8. doi: 10.1080/08941939.2018.1472317. [Epub ahead of print] PubMed PMID: 29846099. 5: Satoh K, Ouchi M, Morita A, Kashimata M. MARCKS phosphorylation and amylase release in GLP-1-stimulated acini isolated from rat pancreas. J Physiol Sci. 2018 May 29. doi: 10.1007/s12576-018-0621-9. [Epub ahead of print] PubMed PMID: 29845509. 6: El-Nassan HB, ElMeshad AN, Wadie W, Sayed RH. Synthesis, Characterization and Biocompatibility of N-palmitoyl L-alanine-based Organogels as Sustained Implants of Granisetron and Evaluation of thier Antiemetic Effect. Pharm Res. 2018 May 29;35(8):149. doi: 10.1007/s11095-018-2433-2. PubMed PMID: 29845459. 7: Niu B, He K, Li P, Gong J, Zhu X, Ye S, Ou Z, Ren G. SIRT1 upregulation protects against liver injury induced by a HFD through inhibiting CD36 and the NF κB pathway in mouse kupffer cells. Mol Med Rep. 2018 May 29. doi: 10.3892/mmr.2018.9088. [Epub ahead of print] PubMed PMID: 29845302. 8: Zhang M, Zhou Y, Peng Y, Jin L. Two rare missense mutations in the fibrillin 1 gene associated with atypical cardiovascular manifestations in a Chinese patient affected by Marfan syndrome. Mol Med Rep. 2018 May 22. doi: 10.3892/mmr.2018.9041. [Epub ahead of print] PubMed PMID: 29845260. 9: Ma L, Huo CY, Zhang XY, Qin CQ, Ren DF, Lu J. Protective effect of Letinous edodes foot peptides against ethanol induced liver injury in L02 cells. Mol Med Rep. 2018 May 29. doi: 10.3892/mmr.2018.9093. [Epub ahead of print] PubMed PMID: 29845248. 10: Nie H, Mei Z, Wang R, Zhao B, Gao Y, Chen J, Wang L. Bushen recipe and its disassembled prescriptions inhibit inflammation of liver injury associated with Concanavalin A through Toll like receptor 3/9 signaling pathway. Mol Med Rep. 2018 May 29. doi: 10.3892/mmr.2018.9082. [Epub ahead of print] PubMed PMID: 29845244. 11: Zhao X, Zhou H, Cheng Y, Yu W, Luo G, Duan C, Yao F, Xiao B, Feng C, Xia X, Wei M, Wang Y, Li J, Dai R. Reduction in activating transcription factor 4 promotes carbon tetrachloride and lipopolysaccharide/D galactosamine mediated liver injury in mice. Mol Med Rep. 2018 May 29. doi: 10.3892/mmr.2018.9080. [Epub ahead of print] PubMed PMID: 29845243. 12: Qasem MA, Noordin MI, Arya A, Alsalahi A, Jayash SN. Evaluation of the glycemic effect of Ceratonia siliqua pods (Carob) on a streptozotocin-nicotinamide induced diabetic rat model. PeerJ. 2018 May 23;6:e4788. doi: 10.7717/peerj.4788. eCollection 2018. PubMed PMID: 29844959; PubMed Central PMCID: PMC5970558. 13: Li Y, Xu H, Wu W, Ye J, Fang D, Shi D, Li L. Clinical application of angiotensin receptor blockers in patients with non-alcoholic fatty liver disease: a systematic review and meta-analysis. Oncotarget. 2018 Jan 2;9(35):24155-24167. doi: 10.18632/oncotarget.23816. eCollection 2018 May 8. PubMed PMID: 29844879; PubMed Central PMCID: PMC5963622. 14: Abdel-Kader MS, Abulhamd AT, Hamad AM, Alanazi AH, Ali R, Alqasoumi SI. Evaluation of the hepatoprotective effect of combination between hinokiflavone and Glycyrrhizin against CCl(4) induced toxicity in rats. Saudi Pharm J. 2018 May;26(4):496-503. doi: 10.1016/j.jsps.2018.02.009. Epub 2018 Feb 11. PubMed PMID: 29844720; PubMed Central PMCID: PMC5962645. 15: Wang R, Wang J, Song F, Li S, Yuan Y. Tanshinol ameliorates CCl(4)-induced liver fibrosis in rats through the regulation of Nrf2/HO-1 and NF-κB/IκBα signaling pathway. Drug Des Devel Ther. 2018 May 17;12:1281-1292. doi: 10.2147/DDDT.S159546. eCollection 2018. PubMed PMID: 29844659; PubMed Central PMCID: PMC5961642. 16: Yang SJ, Kwak SY, Jo G, Song TJ, Shin MJ. Serum metabolite profile associated with incident type 2 diabetes in Koreans: findings from the Korean Genome and Epidemiology Study. Sci Rep. 2018 May 29;8(1):8207. doi: 10.1038/s41598-018-26320-9. PubMed PMID: 29844477. 17: El-Serafi I, Remberger M, El-Serafi A, Benkessou F, Zheng W, Martell E, Ljungman P, Mattsson J, Hassan M. The effect of N-acetyl-l-cysteine (NAC) on liver toxicity and clinical outcome after hematopoietic stem cell transplantation. Sci Rep. 2018 May 29;8(1):8293. doi: 10.1038/s41598-018-26033-z. PubMed PMID: 29844459. 18: Chang C, Amer BR, Osipiuk J, McConnell SA, Huang IH, Hsieh V, Fu J, Nguyen HH, Muroski J, Flores E, Ogorzalek Loo RR, Loo JA, Putkey JA, Joachimiak A, Das A, Clubb RT, Ton-That H. In vitro reconstitution of sortase-catalyzed pilus polymerization reveals structural elements involved in pilin cross-linking. Proc Natl Acad Sci U S A. 2018 May 29. pii: 201800954. doi: 10.1073/pnas.1800954115. [Epub ahead of print] PubMed PMID: 29844180. 19: Callender JA, Yang Y, Lordén G, Stephenson NL, Jones AC, Brognard J, Newton AC. Protein kinase Cα gain-of-function variant in Alzheimer's disease displays enhanced catalysis by a mechanism that evades down-regulation. Proc Natl Acad Sci U S A. 2018 May 29. pii: 201805046. doi: 10.1073/pnas.1805046115. [Epub ahead of print] PubMed PMID: 29844158. 20: Papasergi-Scott MM, Stoveken HM, MacConnachie L, Chan PY, Gabay M, Wong D, Freeman RS, Beg AA, Tall GG. Dual phosphorylation of Ric-8A enhances its ability to mediate G protein α subunit folding and to stimulate guanine nucleotide exchange. Sci Signal. 2018 May 29;11(532). pii: eaap8113. doi: 10.1126/scisignal.aap8113. PubMed PMID: 29844055.