MedKoo Cat#: 562881 | Name: Takeda103A
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Takeda103A is a potent inhibitor of the GRK2--​dependent bovine tubulin oxidation.

Chemical Structure

Takeda103A
Takeda103A
CAS#865609-72-9

Theoretical Analysis

MedKoo Cat#: 562881

Name: Takeda103A

CAS#: 865609-72-9

Chemical Formula: C24H23F2N7O

Exact Mass: 463.1932

Molecular Weight: 463.49

Elemental Analysis: C, 62.19; H, 5.00; F, 8.20; N, 21.15; O, 3.45

Price and Availability

Size Price Availability Quantity
25mg USD 950.00 2 Weeks
50mg USD 1,450.00 2 Weeks
100mg USD 2,250.00 2 Weeks
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Related CAS #
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Synonym
Takeda103A; Takeda-103-A; Takeda 103 A; Takeda-103A; CMPD103A; CMPD-103A; CMPD 103 A; CMPD-103-A;
IUPAC/Chemical Name
N-[(2,6-Difluorophenyl)methyl]-3-[[[4-propyl-5-(4-pyrimidinyl)-4H-1,2,4-triazol-3-yl]methyl]amino]-benzamide
InChi Key
VWBSMGFTNCQOMB-UHFFFAOYSA-N
InChi Code
InChI=1S/C24H23F2N7O/c1-2-11-33-22(31-32-23(33)21-9-10-27-15-30-21)14-28-17-6-3-5-16(12-17)24(34)29-13-18-19(25)7-4-8-20(18)26/h3-10,12,15,28H,2,11,13-14H2,1H3,(H,29,34)
SMILES Code
O=C(NCC1=C(F)C=CC=C1F)C2=CC=CC(NCC3=NN=C(C4=NC=NC=C4)N3CCC)=C2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 463.49 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Waldschmidt HV, Homan KT, Cruz-Rodríguez O, Cato MC, Waninger-Saroni J, Larimore KM, Cannavo A, Song J, Cheung JY, Kirchhoff PD, Koch WJ, Tesmer JJ, Larsen SD. Structure-Based Design, Synthesis, and Biological Evaluation of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors. J Med Chem. 2016 Apr 28;59(8):3793-807. doi: 10.1021/acs.jmedchem.5b02000. Epub 2016 Apr 13. PubMed PMID: 27050625; PubMed Central PMCID: PMC4890168.