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MedKoo Cat#: 596470 | Name: Eptazocine hydrobromide

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Eptazocine hydrobromide is a DG01564 Opioid receptor agonist, DG01562 kappa-Opioid receptor agonist, DG01984 Opioid analgesics, DG01586 Opioid receptor antagonist.

Chemical Structure

Eptazocine hydrobromide
Eptazocine hydrobromide
CAS#72150-17-5

Theoretical Analysis

MedKoo Cat#: 596470

Name: Eptazocine hydrobromide

CAS#: 72150-17-5

Chemical Formula: C15H22BrNO

Exact Mass:

Molecular Weight: 312.25

Elemental Analysis: C, 57.70; H, 7.10; Br, 25.59; N, 4.49; O, 5.12

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Eptazocine hydrobromide; l-ST-2121; MCV 4169; ST-2121; sT 2121, l-; MCV-4169; MCV4169;
IUPAC/Chemical Name
1,4-dimethyl-2,3,4,5,6,7-hexahydro-1H-1,6-methanobenzo[e]azonin-10-ol hydrobromide
InChi Key
KMISFPIWSMSMJD-UHFFFAOYSA-N
InChi Code
InChI=1S/C15H21NO.BrH/c1-15-5-6-16(2)10-11(9-15)7-12-3-4-13(17)8-14(12)15;/h3-4,8,11,17H,5-7,9-10H2,1-2H3;1H
SMILES Code
OC1=CC=C2C(C(C3)(C)CCN(C)CC3C2)=C1.[H]Br
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 312.25 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Mizobe T, Oda Y, Natsuyama T, Miyazaki M. Anesthetic management with eptazocine hydrobromide in patients receiving long-term antipsychotic medication. J Anesth. 1992 Jan;6(1):21-7. PubMed PMID: 15278579. 2: Yanaura S, Kitagawa H, Hosokawa T, Misawa M. [Effects of methanobenzazonine (2,3,4,5,6,7-hexahydro-1,6-methano-1H-4-benzazonine) derivatives on the cough reflex and respiration]. Nihon Yakurigaku Zasshi. 1982 Jul;80(1):43-50. Japanese. PubMed PMID: 7173733. 3: Koizumi T, Kakemi M, Katayama K, Ogawa M. A pharmcokinetic model for enterohepatic circulation of an analgesic l-1,4-dimethyl-10-hydroxy-2,3,4,5,6,7-hexahydro-1,6-methano-1H-4-benzazonine hydrobromide (l-ST-2121) in rats. J Pharmacobiodyn. 1981 Jul;4(7):461-8. PubMed PMID: 7299614. 4: Ogawa M, Nogami Y, Miyamura Y, Kameda S, Tsuji S, Miyamura Y, Miyamoto S, Koizumi T. [Metabolic fate of a new analgesics l-1,4-dimethyl-10-hydroxy-2,3,4,5,6,7-hexahydro-1,6-methano-1H-4-benzazonine hydrobromide (l-ST-2121). III.) Absorption, excretion and metabolism in mouse rat, rabbit, dog, monkey and man (author's transl)]. Yakugaku Zasshi. 1980 Sep;100(9):967-72. Japanese. PubMed PMID: 7218159. 5: Futsukaichi O, Hayashi I, Miyamura Y, Kurobe A, Nozawa T, Miyamoto S, Shiotani S. [Synthesis and analgesic activities of urinary metabolites of a new analgesic (-)-1,4-dimethyl-10-hydroxy-2,3,4,5,6,7-hexahydro-1,6-methano-1H-4-benzazonine hydrobromide (l-ST-2121) in rats (author's transl)]. Yakugaku Zasshi. 1980 May;100(5):509-14. Japanese. PubMed PMID: 7452444. 6: Suzuki T, Izumisawa Y, Nozawa T, Yanaura S. [Physical dependence liability test of l-1, 4-dimethyl-10-hydroxy-2, 3, 4, 5, 6, 7-hexahydro-1, 6-methano-1H-4-benzazonine hydrobromide (l-ST-2121) in rats (author's transl)]. J Toxicol Sci. 1980 May;5(2):163-76. Japanese. PubMed PMID: 7192746. 7: Nogami Y, Miyamura Y, Kurobe A, Ogawa M, Miyamoto S, Koizumi T. [Metabolic fate of a new analgesics 1,4-dimethyl-10-hydroxy-2,3,4,5,6,7-hexahydro-1,6-methano-1H-4-benzazonine hydrobromide (ST-2121). II. Comparative metabolism of the optical isomers in rat urine (author's transl)]. Yakugaku Zasshi. 1980 Apr;100(4):407-14. Japanese. PubMed PMID: 7431213. 8: Nogami Y, Futsukaichi O, Ogawa M, Koizumi T. [Metabolic fate of a new analgesics l-1,4-dimethyl-10-hydroxy-2,3,4,5,6,7-hexahydro-1,6-methano-1H-4-benzazonine hydrobromide (l-ST-2121). I. Absorption, distribution and excretion of l-ST-2121 in rats (author's transl)]. Yakugaku Zasshi. 1979 Jul;99(7):757-64. Japanese. PubMed PMID: 583639.