L-Xylose | CAS#609-06-3 | sugar

MedKoo Cat#: 596418 | Name: L-Xylose

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Description:

WARNING: This product is for research use only, not for human or veterinary use.

L-Xylose is a sugar first isolated from wood, and named for it. Xylose is classified as a monosaccharide of the aldopentose type, which means that it contains five carbon atoms and includes an aldehyde functional group. It is derived from hemicellulose, one of the main constituents of biomass. Like most sugars, it can adopt several structures depending on conditions. With its free aldehyde group, it is a reducing sugar.

Chemical Structure

L-Xylose

CAS#609-06-3

Theoretical Analysis

MedKoo Cat#: 596418

Name: L-Xylose

CAS#: 609-06-3

Chemical Formula: C5H10O5

Exact Mass: 150.0528

Molecular Weight: 150.13

Elemental Analysis: C, 40.00; H, 6.71; O, 53.28

Price and Availability

Size	Price	Availability	Quantity
5g	USD 250.00	2 weeks
25g	USD 550.00	2 weeks

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Synonym

L-Xylose; L(+)-Xylose; EINECS 210-174-1; NSC 26213; NSC-26213; NSC26213;

IUPAC/Chemical Name

(2S,3R,4S)-2,3,4,5-tetrahydroxypentanal

InChi Key

PYMYPHUHKUWMLA-WISUUJSJSA-N

InChi Code

InChI=1S/C5H10O5/c6-1-3(8)5(10)4(9)2-7/h1,3-5,7-10H,2H2/t3-,4+,5+/m1/s1

SMILES Code

O=C[C@H]([C@@H]([C@H](CO)O)O)O

Appearance

Solid powder

Purity

>97% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

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Product Data

Product Data

Instruction

View handling instruction

Biological target:

L-Xylose (L-(-)-Xylose) is the levo-isomer of Xylose.

In vitro activity:

The iso-molar addition of either 100 mM sorbitol, L-xylose, or lactose in mucosal buffer fluid increased the absorptive flux of Ca from mucosa to serosa to a similar extent and thus reversed ileal net Ca transport from net secretion to a zero net movement. In conclusion, the present result shows that sorbitol, L-xylose, and lactose increase net Ca absorption to a comparable extent, in the absence of electrochemical or osmotic gradients. Reference: Miner Electrolyte Metab. 1995;21(6):391-7. https://pubmed.ncbi.nlm.nih.gov/8592482/

In vivo activity:

Xylose improves the antibiotic activity of tetracycline and chloramphenicol against efflux-mediated resistance Acinetobacter baumannii and Klebsiella pneumoniae, in a murine model of skin infection. Reference: Can J Infect Dis Med Microbiol. 2018 Jul 18;2018:3467219. https://pubmed.ncbi.nlm.nih.gov/30123393/

	Solvent	mg/mL	mM
Solubility
	DMSO	100.0	666.09

Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 150.13 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Formulation protocol:

1. Lacour B, Ohan J, Aznag A, Drüeke TB. Stimulating effects of sorbitol and L-xylose on rat ileal Ca transport in vitro. Miner Electrolyte Metab. 1995;21(6):391-7. PMID: 8592482. 2. Hidalgo AA, Arias ÁJ, Fuentes JA, García P, Mora GC, Villagra NA. Xylose Improves Antibiotic Activity of Chloramphenicol and Tetracycline against K. pneumoniae and A. baumannii in a Murine Model of Skin Infection. Can J Infect Dis Med Microbiol. 2018 Jul 18;2018:3467219. doi: 10.1155/2018/3467219. PMID: 30123393; PMCID: PMC6079543.

In vitro protocol:

Lacour B, Ohan J, Aznag A, Drüeke TB. Stimulating effects of sorbitol and L-xylose on rat ileal Ca transport in vitro. Miner Electrolyte Metab. 1995;21(6):391-7. PMID: 8592482.

In vivo protocol:

Hidalgo AA, Arias ÁJ, Fuentes JA, García P, Mora GC, Villagra NA. Xylose Improves Antibiotic Activity of Chloramphenicol and Tetracycline against K. pneumoniae and A. baumannii in a Murine Model of Skin Infection. Can J Infect Dis Med Microbiol. 2018 Jul 18;2018:3467219. doi: 10.1155/2018/3467219. PMID: 30123393; PMCID: PMC6079543.

1: Meng Q, Zhang T, Jiang B, Mu W, Miao M. Advances in applications, metabolism, and biotechnological production of L-xylulose. Appl Microbiol Biotechnol. 2016 Jan;100(2):535-40. doi: 10.1007/s00253-015-7087-y. Epub 2015 Nov 3. Review. PubMed PMID: 26526452. 2: Chu CK, Boudinot FD, Peek SF, Hong JH, Choi Y, Korba BE, Gerin JL, Cote PJ, Tennant BC, Cheng YC. Preclinical investigation of L-FMAU as an anti-hepatitis B virus agent. Antivir Ther. 1998;3(Suppl 3):113-21. Review. PubMed PMID: 10726061.