Metipranolol hydrochloride is a non-selective β-adrenergic receptor (β-AR) antagonist. Formulations containing metipranolol have been used in the treatment of elevated IOP in patients with ocular hypertension or glaucoma.
MedKoo Cat#: 584448
Name: Metipranolol hydrochloride
CAS#: 36592-77-5 (HCl)
Chemical Formula: C17H28ClNO4
Exact Mass: 345.1707
Molecular Weight: 345.86
Elemental Analysis: C, 59.04; H, 8.16; Cl, 10.25; N, 4.05; O, 18.50
| Solvent | mg/mL | mM | comments | |
|---|---|---|---|---|
| Solubility | ||||
| DMF | 50.0 | 144.57 | ||
| DMSO | 75.0 | 216.85 | ||
| Ethanol | 10.0 | 28.91 | ||
| PBS (pH 7.2) | 5.0 | 14.46 | ||
| Water | 100.0 | 289.13 |
The following data is based on the product molecular weight 345.86 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
