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MedKoo Cat#: 591207 | Name: ADR-851 HCl

Description:

WARNING: This product is for research use only, not for human or veterinary use.

ADR-851 HCl is an HT3 receptor antagonist. It works against acute thermal, mechanical and formalin-induced inflammatory pain.

Chemical Structure

ADR-851 HCl
CAS#123805-17-4 (HCl)

Theoretical Analysis

MedKoo Cat#: 591207

Name: ADR-851 HCl

CAS#: 123805-17-4 (HCl)

Chemical Formula: C14H19Cl2N3O2

Exact Mass: 331.0854

Molecular Weight: 332.23

Elemental Analysis: C, 50.61; H, 5.76; Cl, 21.34; N, 12.65; O, 9.63

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Adr 851; Adr-851; Adr851;
IUPAC/Chemical Name
7-Benzofurancarboxamide, 4-amino-5-chloro-2,3-dihydro-N-(2-pyrrolidinylmethyl)-, monohydrochloride, (S)-
InChi Key
PCBGZTCWZUGEJX-QRPNPIFTSA-N
InChi Code
InChI=1S/C14H18ClN3O2.ClH/c15-11-6-10(13-9(12(11)16)3-5-20-13)14(19)18-7-8-2-1-4-17-8;/h6,8,17H,1-5,7,16H2,(H,18,19);1H/t8-;/m0./s1
SMILES Code
O=C(C1=C(OCC2)C2=C(N)C(Cl)=C1)NC[C@H]3NCCC3.[H]Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 332.23 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Sufka KJ, Giordano J. Analgesic effects of S and R isomers of the novel 5-HT3 receptor antagonists ADR-851 and ADR-882 in rats. Eur J Pharmacol. 1991 Oct 29;204(1):117-9. PubMed PMID: 1804661. 2: Rossi DT, Overmyer SK, Lewis RC, Narang PK. Quantitation of a novel antiemetic (ADR-851) in plasma and urine by reversed-phase high-performance liquid chromatography with fluorescence detection. J Chromatogr. 1991 May 3;566(1):257-65. PubMed PMID: 1885720.