MedKoo Cat#: 596261 | Name: Iodamide

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Iodamide is a molecule used as a contrast medium.

Chemical Structure

Iodamide
Iodamide
CAS#440-58-4 (free base)

Theoretical Analysis

MedKoo Cat#: 596261

Name: Iodamide

CAS#: 440-58-4 (free base)

Chemical Formula: C12H11I3N2O4

Exact Mass: 627.7853

Molecular Weight: 627.94

Elemental Analysis: C, 22.95; H, 1.77; I, 60.63; N, 4.46; O, 10.19

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Synonym
Iodamide; Uromiro; Urombrine; Ametriiodic acid; ametriodinic acid; Ametriiodinic acid; Iodamida; Uromiron; Iodamidum
IUPAC/Chemical Name
3-acetamido-5-(acetamidomethyl)-2,4,6-triiodobenzoic acid
InChi Key
VVDGWALACJEJKG-UHFFFAOYSA-N
InChi Code
InChI=1S/C12H11I3N2O4/c1-4(18)16-3-6-8(13)7(12(20)21)10(15)11(9(6)14)17-5(2)19/h3H2,1-2H3,(H,16,18)(H,17,19)(H,20,21)
SMILES Code
O=C(O)C1=C(I)C(CNC(C)=O)=C(I)C(NC(C)=O)=C1I
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 627.94 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Kamesh Iyer S, Tasdizen T, Dibella EV. Edge-enhanced spatiotemporal constrained reconstruction of undersampled dynamic contrast-enhanced radial MRI. Magn Reson Imaging. 2012 Jun;30(5):610-9. doi: 10.1016/j.mri.2011.12.021. Epub 2012 Mar 28. PubMed PMID: 22459444; PubMed Central PMCID: PMC3593596. 2: Mohd Nor H, Jayapragasam K, Abdullah B. Diagnostic image quality of hysterosalpingography: ionic versus non ionic water soluble iodinated contrast media. Biomed Imaging Interv J. 2009 Jul;5(3):e29. doi: 10.2349/biij.5.3.e29. Epub 2009 Jul 1. PubMed PMID: 21611058; PubMed Central PMCID: PMC3097785. 3: Ramponi S, Grotti A, Morisetti A, Vultaggio S, Lorusso V. Effects of iodinated contrast media on endothelium: An in vitro study. Toxicol In Vitro. 2007 Mar;21(2):191-6. Epub 2006 Oct 1. PubMed PMID: 17113744. 4: Valentini AL, De Gaetano AM, Minordi LM, Nanni G, Citterio F, Viggiano AM, Tancioni V, Destito C. Contrast-enhanced voiding US for grading of reflux in adult patients prior to antireflux ureteral implantation. Radiology. 2004 Oct;233(1):35-9. Epub 2004 Aug 18. PubMed PMID: 15317946. 5: Napolov IuK, Shimanovskiĭ NL. [The effect of diagnostic contrast media on the activity of lactate dehydrogenase in rat blood]. Eksp Klin Farmakol. 2002 Jul-Aug;65(4):59-65. Russian. PubMed PMID: 12449078. 6: Sergeev PV, Sviridov NK, Poliaev IuA, Shimanovskiĭ NL. [Diagnostic effectiveness and safety of currently available X-ray contrast media]. Vestn Rentgenol Radiol. 1999 Nov-Dec;(6):45-9. Review. Russian. PubMed PMID: 10714233. 7: Wu D, Berna M, Maier G, Johnson J. An automated multidimensional screening approach for rapid method development in high performance liquid chromatography. J Pharm Biomed Anal. 1997 Sep;16(1):57-68. PubMed PMID: 9447552. 8: Caprino L, Togna AR, Zappacosta B, Giardina B, Togna G. Modulation of ADPase and t-PA release by radiographic contrast media in bovine aortic endothelium. Pharmacol Res. 1997 May;35(5):429-33. PubMed PMID: 9299206. 9: Napolov IuK. [The effect of epsilon-aminocaproic acid and prednisolone on the activation of the complement system due to x-ray contrast agents in rats in vitro]. Eksp Klin Farmakol. 1997 Mar-Apr;60(2):62-4. Russian. PubMed PMID: 9206574. 10: Napolov IuK. [The mechanism of histamine liberation from rat mast cells under the action of x-ray contrast media]. Eksp Klin Farmakol. 1997 Jan-Feb;60(1):53-5. Russian. PubMed PMID: 9162287. 11: Pavone P, Pizzamiglio M, Catalano C, Sarrantonio A, Pronio A, Montesani C, Ribotta G, Passariello R. [Restorative proctocolectomy. A morphological-functional study by computed tomography with coronal scans]. Radiol Med. 1995 Sep;90(3):244-9. Italian. PubMed PMID: 7501829. 12: Ul'ianov GP. [The effect of cimetidine on the renal excretion of verografin and iodamide in dogs]. Eksp Klin Farmakol. 1994 Nov-Dec;57(6):53-4. Russian. PubMed PMID: 7756965. 13: Podshivalov BV, Zhuravlev PA, Aldongarov GB, Ushakov SA. [Use of iodamide 300 and iodamide 380 in galactography]. Vestn Rentgenol Radiol. 1994 Jan-Feb;(1):37-8. Russian. PubMed PMID: 7975160. 14: Urrutia M, Macharaviaya A, Rodríguez R. [Adverse reactions to high osmolarity contrast media. A comparative-prospective study]. Rev Med Panama. 1994 Jan;19(1):19-26. Spanish. PubMed PMID: 7938712. 15: Napolov IuK, Shimanovskiĭ NL, Bolotova EN, Borsukova NM, Sergeev PV. [The effect of x-ray contrast media on the amount of thromboxane and prostacyclin in the blood of man and rats in vivo and in vitro]. Eksp Klin Farmakol. 1993 Sep-Oct;56(5):41-3. Russian. PubMed PMID: 8312809. 16: Zaretskiĭ DV, Troianovskaia LB, Garin VR. [The possible mechanisms of the interaction of hepatotropic diagnostic agents with proteins]. Eksp Klin Farmakol. 1992 Nov-Dec;55(6):43-6. Russian. PubMed PMID: 1305876. 17: Napolov IuK, Borsukova NM, Shimanovskiĭ NL. [Effects of contrast media on interleukin-2 levels in human plasma in vitro]. Biull Eksp Biol Med. 1992 Sep;114(9):288-90. Russian. PubMed PMID: 1477362. 18: Rosati G, Leto di Priolo S, Tirone P. Serious or fatal complications after inadvertent administration of ionic water-soluble contrast media in myelography. Eur J Radiol. 1992 Sep;15(2):95-100. PubMed PMID: 1425760. 19: Aronen HJ, Kivisaari L, Torstila I, Paavonen T, Meri S, Karonen SL, Standertskjöld-Nordenstam CG. Level of plasma prekallikrein and its inhibitors in reactors and nonreactors during intravenous enhancement with contrast media. Acta Radiol. 1992 Jul;33(4):374-8. PubMed PMID: 1378750. 20: Ammann ME, Winkelbauer F, Fitzal P. [The urethrocystogram and perineal sonography compared]. Rofo. 1992 Apr;156(4):309-12. German. PubMed PMID: 1315170.